Acta Scientific Orthopaedics (ISSN: 2581-8635)

Research Article Volume 5 Issue 8

Viral Activity Among Incidentally Detected Asymptomatic HBSAG Positive Patients in Khartoum State

Abdelsalam Mohamed Ahmed1, Mohamed Kharief2, Ayoub Mustafa Omar Ali3, Musaab Mohamed Abdallah4* and Mohamed Alkhatem5

1MBBS MD MSc FRCP, Associate Professor of Internal Medicine, Department of Internal Medicine, Faculty of Medicine and Health Sciences (OIU), Sudan
2Registrar of Internal Medicine, Sudan
3MBBS, MD Internal Medicine, Sudan
4MD Orthopaedics Associate department Karary University, Sudan
5MBBS, MD Orthopaedics, Department Karary University, Sudan

*Corresponding Author: MBBS, MD Orthopaedics, Associate Professor Karary University, Sudan.

Received: May 11, 2022; Published: July 15, 2022

One of the commonest modes of detection of hepatitis-B virus (HBV) infection is incidental detection. Incidentally detected asymptomatic HBsAg (IDAHS) positive patients represent a heterogeneous group with variable serological and clinical profile. The aim is to study the viral activity of IDAHS positive patients.

Keywords:Asymptomatic HBSAG; Positive Patients; Viral Activity

References

  1. Abbas Z and Siddiqui AR. “Management of hepatitis B in developing countries”. World Journal of Hepatology 12 (2011): 292.
  2. Lok ASF and McMahon BJ. “Chronic hepatitis B”. Hepatology 2 (2007): 507-539.
  3. Mudawi H. “Epidemiology of viral hepatitis in Sudan”. Clinical and Experimental Gastroenterology 1 (2008): 9.
  4. Shiha G., et al. “Characterization of incidentally detected asymptomatic hepatitis B positive subjects in Egypt”. Bangladesh Liver Journal1 (2009): 20-27.
  5. Dixit VK and Jena SK. “Incidentally detected asymptomatic HBsAg positive subjects”. Hepatitis B - Annual 1 (2008): 95.
  6. Hsu YS., et al. “Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B”. Hepatology6 (2002): 1522-1527.
  7. Bortolotti F., et al. “Outcome of chronic hepatitis B in Caucasian children during a 20-year observation period”. Journal of Hepatology 2 (1998): 184-190.
  8. Kreutz C. “Molecular, immunological and clinical properties of mutated hepatitis B viruses”. Journal of Cellular and Molecular Medicine 1 (2002): 113.
  9. Ter Borg F., et al. “Relation between laboratory test results and histological hepatitis activity in individuals positive for hepatitis B surface antigen and antibodies to hepatitis B e antigen”. Lancet (London, England) 351 (9120): 1914-1918.
  10. Liaw YF. “HBeAg seroconversion as an important end point in the treatment of chronic hepatitis B”. Hepatology International 3 (2009): 425.
  11. Badawi MM., et al. “A Diagnostic Laboratory-Based Study on Frequency and Distribution of Viral Hepatitis B and C Among Sudanese”. The Open Virology Journal 1 (2017): 98.
  12. Choudhuri G., et al. “Potential Implications of Detecting HBsAg in Asymptomatic People in an Endemic Community Through Medical Camps”. Journal of Clinical and Experimental Hepatology 1 (2019): 43-49.
  13. Arora D., et al. “Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana”. Indian Journal of Pathology and Microbiology 2 (2010): 308-309.
  14. Unnikrishnan B., et al. “Profile of blood donors and reasons for deferral in coastal South India”. Australasian Medical Journal 7 (2011): 379-385.
  15. Chen C-J., et al. “Hepatocellular carcinoma occurred in a Hepatitis B carrier clinic cohort during a mean follow up of 10 years”. Hepatoma Research 5 (2019): 25.
  16. Khokhar N and Gill ML. “Serological profile of incidentally detected asymptomatic HBsAg positive subjects (IDAHS)”. Journal of College of Physicians and Surgeons Pakistan 4 (2004): 208-210.
  17. Kashif M., et al. “Serological markers of hepatitis B infection in incidentally Incidentally Detected HBsAg Positive Patients”. Proceedings of Shaikh Zayed Postgraduate Medical Institute 0 (2006): 93-97.
  18. Chu CM and Liaw YF. “HBsAg seroclearance in asymptomatic carriers of high endemic areas: Appreciably high rates during a long-term follow-up”. Hepatology 5 (2007): 1187-1192.
  19. Chu CJ., et al. “Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C”. Gastroenterology 7 (2002): 1756-1762.
  20. Chandra R., et al. “Profile of asymptomatic chronic HBV infection in India”. Indian Journal of Medical Research 6 (2002): 50-57.
  21. Yousif M., et al. “Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan”. BMC Infectious Diseases 1 (2013): 1-11.
  22. Girotra M and Arora A. “IDAHS (Incidentally Detected Asymptomatic HbsAg-positive Subjects): Clinical and Serological Overview”. The American Journal of Gastroenterology 5 (2010): S95.
  23. Martín-Vílchez S., et al. “Effects of hepatitis B virus X protein on chronic hepatitis B pathophysiology”. Medicina Clínica (Barc)11 (2012): 508-513.
  24.  

Citation

Citation: Musaab Mohamed Abdallah., et al. “Viral Activity Among Incidentally Detected Asymptomatic HBSAG Positive Patients in Khartoum State". Acta Scientific Orthopaedics 5.8 (2022): 71-77.

Copyright

Copyright: © 2022 Musaab Mohamed Abdallah., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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