Vitamin K and Osteoarthritis Associated Observations: “What’s New” in 2022
Single Incision Department of Health and Behavior Studies, Teachers College, Columbia University, New York, United States
*Corresponding Author: Ray Marks, Department of Health and Behavior Studies, Teachers College, Columbia University, New York, United States.
June 30, 2022; Published: July 12, 2022
Osteoarthritis, the most common joint disease experienced by many older adults and one that is increasing as societies age remains largely incurable and highly disabling. As such, and in light of the failure of most palliative pharmacologic strategies to date to reverse or mitigate this painful condition, it appears all avenues of potential progress added to those already being explored may yet prove fruitful. Based on emerging and quite promising data outlining a possible link between aspects of osteoarthritis joint damage and vitamin K serum deficits, this mini-review elected to examine the most current data in regard to whether: 1) Vitamin K, an important dietary compound is being shown to be a potentially valuable health determinant whose presence might influence the onset and progression of osteoarthritis through direct as well as indirect pathways, and 2) any evidence pointing to its possible supplementation as being desirable in this regard if indicated. Based on the bulk of available data housed in PUBMED as of June 25, 2022, it is concluded that a mediating or moderating role for vitamin K in the realm of osteoarthritis cannot be ignored. Future efforts to advance this line of inquiry from multiple perspectives may hence prove highly fruitful in efforts to prevent or reduce osteoarthritis disability and its immense personal and socioeconomic costs.
Keywords: Aging; Bone; Cartilage; Osteoarthritis; Pathology; Prevention; Vitamin K
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