Acta Scientific Orthopaedics (ISSN: 2581-8635)

Research Article Volume 5 Issue 7

Demographic Characteristics, Anatomical Distribution and Presentation of Sudanese Patients with Giant Cell Tumor

Hassan Mohammed Hassan Elbahri1, Ali Hamid Ali Osman2, Hozifa Mohammed Ali Abd-Elmaged3* and Hassan EHM Ahmed4

1Associated Professor of Orthopedic Oncology, Department of Orthopedic International University of Africa - Khartoum, Sudan
2Orthopedics and Trauma Surgeon, Khartoum North Teaching Hospital, Sudan
3Assistant Professor of Orthopedic, Fellow of Orthopedic Oncology, Department of Orthopedic Al-Zaiem Al-Azhari University- Khartoum, Sudan
4Department of Human Anatomy, Faculty of Medicine and Health Science, Omdurman Islamic University, Department of Orthopedic Surgery, Sudanese Medical Research Association, Sudan

*Corresponding Author: Hozifa Mohammed Ali Abd-Elmaged, Assistant Professor of Orthopedic, Fellow of Orthopedic Oncology, Department of Orthopedic Al-Zaiem Al-Azhari University- Khartoum, Sudan.

Received: May 20, 2022; Published: June 15, 2022

Abstract

Introduction: Giant cell tumor of bone (GCTB) is a benign aggressive primary bone tumor. This study provides an overview of demographics, anatomical distribution, and clinical presentation of GCTB in Sudan.

Material and Methods: This retrospective study was conducted on patients with a diagnosis of giant cell tumor of the bone that attended our institution.  Demographic information, tumor location and clinical presentation were obtained from medical records of patients. Data were collected using data sheet and analyzed using statistical package for social science (SPSS version 26).

Result: This study include 46 patients diagnosed with giant cell tumor of bone, 34 male (73.9%) and 12 female (26.1%), with their ages ranging from 17 - 57 years old, patients with age 30 or less are 31 (67.4%), age from 31 to 50 years are 12 (26.1%), and patients age more than 50 are 3 (6.5%), the mean age being 26.5 years old. The location of tumor was found to be commonly in proximal tibia 21 (45.7%) patients, followed by distal femur 18 (39.1%) patients, then distal tibia 3 (6.5%) patients, proximal fibula 1 (2.17%), patella 1 (2.17%) patient, calcaneum 1 (2.17%) patient and distal humerus 1 (2.17%) patient. All patients (100%) presented with pain that affect their life activity.

Conclusion: This study demonstrates an overview of GCTB in Sudan. Male was predominating over female in this study which is opposing the previous studies. Age distribution show slightly difference from those data in literature. In our patients, the tumor location and clinical presentation was in line with previous study. Further studies are recommended to expand information about GCT in Sudan.

Keywords: Giant Cell Tumor of Bone; Demographics; Clinical Presentation; Sudan

References

  1. Eckardt JJ and Grogan TJ. “Giant cell tumor of bone”. Clinical Orthopaedics and Related Research 204 (1986): 45-58.
  2. Review CC. “Giant Cell Tumor of Bone - An Overview”. The Archives of Bone and Joint Surgery 2 (2016): 2-9.
  3. Schwab JH., et al. “Giant Cell Tumor of Bone Abstract” 118-26.
  4. Justyna M Amelio., et al. “Population-based study of giant cell tumor of bone in Sweden (1983 - 2011)”. Cancer Epidemiology 42 (2016): 82-89.
  5. Manaster BJ and Doyle AJ. “Giant cell tumors of bone”. Radiologic Clinics of North America 2 (1993): 299-323.
  6. Peimer CA., et al. “Multicentric giant-cell tumor of bone”. The Journal of Bone and Joint Surgery 4 (1980): 652-656.
  7. Mbchb AZ., et al. “Giant cell tumour of bone: A demographic study from a tumour unit in South Africa” 15.4 (2016): 17-22.

Citation

Citation: Hozifa Mohammed Ali Abd-Elmaged., et al. “Demographic Characteristics, Anatomical Distribution and Presentation of Sudanese Patients with Giant Cell Tumor".Acta Scientific Orthopaedics 5.7 (2022): 85-88.

Copyright

Copyright: © 2022 Hozifa Mohammed Ali Abd-Elmaged., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days

Indexed In



News and Events


Contact US