Vitamin K, Osteoporosis, and Hip Fragility Fractures: A Review of Vitamin K Bone Impacts
Ray Marks*
Department of Health and Behavior Studies, Teachers College, Columbia University, New York, United States
*Corresponding Author: Ray Marks, Department of Health and Behavior Studies, Teachers College, Columbia University, New York, United States.
Received:
April 04, 2022; Published: April 21, 2022
Abstract
Hip fragility fractures, which are very common injuries sustained by many older adults commonly lead to disabling hip joint osteoarthritis, premature death, or reduced life quality. As such and given the failure of most hip fracture preventive strategies to date, it appears more might be done to consider incorporating additional strategies into those already in place. This mini review examines whether: 1) Vitamin K, an important dietary compound that can also be partially synthesized intrinsically is a potentially important bone building or modeling determinant whose presence might influence the onset and progression of osteoporosis a key determinant of fragility fractures and 2) whether any evidence points to its application as being desirable among vulnerable aging adults with low vitamin K status or at risk for fragility fractures for other reasons. Based on the bulk of available data housed in PUBMED, it appears that vitamin K and its derivatives do have some promising albeit unproven impacts on bone metabolism, and hence possibly on osteoporosis, a pathological feature often found to prevail in hip fragility fracture injuries. It also appears that in addition to ensuring aging at risk adults have adequate vitamin K intakes and serum levels, efforts to solidify this promising line of inquiry may prove highly fruitful in efforts to prevent or reduce the persistent global age-associated hip fracture burden and its immense associated human and socioeconomic costs and ramifications.
Keywords: Bone Health; Fractures; Fragility; Hip Fractures; Osteoporosis; Prevention, Vitamin K
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