Acta Scientific Orthopaedics (ISSN: 2581-8635)

Review Article Volume 5 Issue 5

The Use of Allograft in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis

Kedar Padhye3*, Jonathan Howatt1, Andrew Gilyan2, Ron EL-Hawary3 and Benjamin Orlik3

1Department of Orthopaedics, University of Ottawa, Ottawa, Ontario, Canada
2Department of Physiology and Biophysics/Department of Neuroscience, Dalhousie University Halifax, Nova Scotia, Canada
3Division of Orthopaedics, IWK Health Centre, Halifax, Nova Scotia, Canada

*Corresponding Author: Kedar Padhye, Division of Orthopaedics, IWK Health Centre, Halifax, Nova Scotia, Canada.

Received: January 28, 2022; Published: April 12, 2022


Posterior spinal instrumentation and fusion (PSIF), with bone grafting, is the most accepted surgical treatment in Adolescent Idiopathic Scoliosis (AIS). Many different options are used as a bone graft, but the difference in the rate of infection and pseudoarthrosis has not been fully documented. This study aimed to compare the outcomes of the use of the allograft in adolescent idiopathic scoliosis (AIS) compared to no graft or autograft alone. A literature search was performed in PubMed, EMBASE, CINAHL, CENTRAL, and Web of Science, using the set inclusion/extrusion criteria. A meta-analysis was performed on select articles with RevMan TM (Review Manager 5) software. Six studies were included for each outcome. In total, the odds of getting a pseudoarthrosis if allograft was used were 1.1 (95% CI: 0.41, 3.09) times the odds of getting a pseudoarthrosis if allograft was not used, which was not statistically significant (p = 0.81). The odds of getting an infection if allograft was used were 1.2 (95% CI: 0.33, 4.72) times the odds of getting an infection if allograft was not used, which was not statistically significant (p = 0.74). There is limited evidence to either strongly support using, or not using allograft bone graft for posterior spinal fusion in cases of AIS when compared to the use of autograft alone or no graft.

Keywords: Adolescent Idiopathic Scoliosis; Posterior Spinal Instrumentation; Fusion; Allograft; Autograft; Pseudoarthrosis; Infection


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Citation: Kedar Padhye., et al. “The Use of Allograft in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis".Acta Scientific Orthopaedics 5.5 (2022): 47-52.


Copyright: © 2022 Kedar Padhye., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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