Bocharov SN*, Bocharova YuS, Mankov AV, Golub IE and Sorokina LV

Irkutsk State Medical University, Irkutsk, Russia

*Corresponding Author: Bocharov SN, Irkutsk State Medical University, Irkutsk, Russia.

Received: October 20, 2021; Published: December 22, 2021

Abstract

Topicality: The key link in the perioperative period of treatment of patients with various pathologies and, especially, all kinds of shock states, is infusion-transfusion therapy, the effectiveness of which depends on the functional state of transcapillary metabolism, determined by the value of oncotic plasma pressure - a derivative of the concentration of Total Protein, and not albumin!.

The traditional method of correction of hypovolemia/blood loss of any genesis and any volume remains hypervolemic hemodilution, accompanied by excessive administration of crystalloid(Na containing) and artificial colloidal solutions, at the same time, neither the sector of their stay is taken into account, nor the volemic coefficient, nor the features of their clinical manifestation are taken into account and ted.

Work: Development of a program for replenishing hypovolemia/hemorrhage, based on the principle of normalization of transcapillary metabolism and the justification of infusion solutions used to correct it. Material and Methods: Based on the analysis of infusion media used in the 30-year period of perioperative treatment of surgical and trauma patients, development and justification of the principles of the program of replenishment of blood loss/hypovolemia, based on the normalization of transcapillary metabolism. Criteria for the effectiveness of treatment, an algorithm for correcting blood loss/hypovolemia are formulated and substantiated. According to the results of a comparative analyzes obtained when performing hemihepathecomy confirmed the high clinical effectiveness of the method of blood loss correction based on the normalization of transcapillary metabolism. This method was used and improved by techniques: preoperative blood procurement and postoperative return of drainage blood in the 20-year period of treatment of trauma patients.

Conclusion: According to the results of the performed studies, high clinical efficacy has been proven and undeniable advantage, which was as follows: patients who underwent hemihepatectomy were discharged with recovery, and 20 years of experience in the practical use of this program in trauma patients confirmed the absolute effectiveness of and security.

Keywords: Total Protein; Albumin; Oncotic Pressure Hypervolemia; Transcapillary Metabolism; Infusion Media

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Citation

Citation: Bocharov SN., et al. “Infusion Media. When? What and How Much?".Acta Scientific Orthopaedics 5.1 (2022): 31-39.

Copyright

Copyright: © 2022 Bocharov SN., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.