Acta Scientific Orthopaedics (ISSN: 2581-8635)

Case Report Volume 4 Issue 7

Recycled Diseased Bone and Morselized Bone Graft: A Unique Combination in the Treatment of Osteosarcoma

Gayathri P Arumugam1*, Dinesh Noel Gomez1 and Vivek Ajit Singh2

1Ministry of Health, Malaysia
2University Malaya Medical Centre, Malaysia

*Corresponding Author: Gayathri P Arumugam, Department of Orthopaedics, Ministry of Health, Malaysia.

Received: May 15, 2021; Published: June 04, 2021


  Osteosarcoma of the distal tibia is a rare occurrence, and the treatment method often poses a dilemma to Orthopaedic Oncology surgeons worldwide. We introduce a unique combination of treatment modalities as a limb salvage technique for a patient diagnosed with osteosarcoma of the distal tibia. Miss T, an 8 year old was diagnosed with Osteosarcoma of the distal tibia. We proceeded with excision of the diseased bone segment and recycled the excised bone via pasteurisation. She was then started on chemotherapy. However, she did not show signs of union, which prompted us to intervene surgically in a 3 stage procedure. The recycled bone fragment was removed, and a cement spacer was inserted temporarily. After a duration of 3 months, we removed the cement spacer and inserted morselized bone graft obtained from bone bank. She started showing signs of union, and her recovery was unperturbed. We believe this combination of treatment to be a successful treatment modality but requires careful and meticulous selection of eligible patients.

Keywords: Osteosarcoma; Limb Salvage; Pasteurization; Morselized Bone Graft


  1. Manabe Jun., et al. “Pasteurized Autologous Bone Graft in Surgery for Bone and Soft Tissue Sarcoma”. Clinical Orthopaedics and Related Research 419 (2004).
  2. Abdel Rahman Mohamed., et al. “Reimplantation of the Resected Tumour-Bearing Segment after Recycling Using Liquid Nitrogen for Osteosarcoma”. International Orthopaedics5 (2009).
  3. Lee SH., et al. “Prosthetic Reconstruction for Tumours of the Distal Tibia and Fibula”. The Journal of Bone and Joint Surgery5 (1999).
  4. Yasin Nor Faissal., et al. “Which Is the Best Method of Sterilization for Recycled Bone Autograft in Limb Salvage Surgery: A Radiological, Biomechanical and Histopathological Study in Rabbit”. BMC Cancer1 (2015).
  5. Natarajan Mayil v., et al. “Limb Salvage in Distal Tibial Osteosarcoma Using a Custom Mega Prosthesis”. International Orthopaedics5 (2000).


Citation: Gayathri P Arumugam., et al. “Recycled Diseased Bone and Morselized Bone Graft: A Unique Combination in the Treatment of Osteosarcoma".Acta Scientific Orthopaedics 4.7 (2021): 16-18.


Copyright: © 2021 Gayathri P Arumugam., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate33%
Acceptance to publication20-30 days

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 20, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US