Gulshan Barwar*

Consultant, Department of Vitreo-Retina Services, Sankara Eye Hospital, Jaipur, India

*Corresponding Author: Gulshan Barwar, Consultant, Department of Vitreo-Retina Services, Sankara Eye Hospital, Jaipur, India.

Received: August 29, 2025; Published: October 26, 2025

Abstract

This is a case report of a 35-year-old female who developed severe systemic and ocular complications following blood transfusion. The patient presented with phthisis bulbi in the right eye and optic atrophy with a full-thickness macular hole in the left eye after TRALI. Additionally, she developed black gangrenous digits in all four limbs.

Ocular complications following TRALI are extremely rare. This case highlights potential mechanisms including vascular occlusion, ocular ischemic syndrome, and retinal atrophy, which may contribute to such outcomes. To our knowledge, this is the first report of its kind.

 Keywords: Transfusion-Related Acute Lung Injury (TRALI); Eye

References

1. Akritidou F., et al. “Ocular manifestations in patients with transfusion-dependent β-thalassemia”. Hippokratia2 (2021): 79-82.
2. Liaska A., et al. “β-Thalassemia and ocular implications: a systematic review”. BMC Ophthalmology 16 (2016): 102.

Citation

Citation: Gulshan Barwar. “TRALI Associated Ocular Complications: A Rare Entity".Acta Scientific Ophthalmology 8.11 (2025): 08-10.

Copyright

Copyright: © 2025 Gulshan Barwar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.