Parth Sharma¹ *, Pooja Goyal² and Sushant Joshi³

¹ MS ENT Resident, Department of Otolaryngology–Head and Neck Surgery, Ananta Institute of Medical Sciences and Research Center, India
² Senior Resident, Department of Otolaryngology–Head and Neck Surgery, Ananta Institute of Medical Sciences and Research Center, India
³ Professor, Department of Otolaryngology–Head and Neck Surgery, Ananta Institute of Medical Sciences and Research Center, India

*Corresponding Author: Parth Sharma, MS ENT Resident, Department of Otolaryngology–Head and Neck Surgery, Ananta Institute of Medical Sciences and Research Center, India.

Received: February 06, 2026; Published: February 20, 2026

Hurler syndrome (mucopolysaccharidosis type I) is a rare autosomal recessive lysosomal storage disorder caused by a deficiency of the enzyme α-L-iduronidase, resulting in progressive accumulation of dermatan and heparan sulfate. Although the disorder is classically associated with skeletal dysplasia, neurodevelopmental delay, and multisystem involvement, otorhinolaryngological manifestations frequently represent the earliest presenting features. We report a rare case of a 5-year-old male child presenting with nasal obstruction due to bilateral antrochoanal polyps, subsequently diagnosed as Hurler syndrome. This case highlights the importance of early ENT recognition of systemic metabolic disorders and emphasises the role of the otorhinolaryngologist in early diagnosis and multidisciplinary management.

Keywords: Hurler Syndrome; Mucopolysaccharidosis Type I; Antrochoanal Polyp; Nasal Polyposis; ENT Manifestations; Glycosaminoglycans

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Citation

Citation: Parth Sharma.,et al. “Bilateral Antrochoanal Polyps in Hurler Syndrome: A Rare ENT Presentation of Mucopolysaccharidosis Type I". Acta Scientific Women's Health 8.3 (2026): 02-06.

Copyright

Copyright: © 2026 Parth Sharma.,et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.