Sachin Gandhi¹, Shradha Saindani²*, Renuka Mundalik³ and Vishakh Nair³

¹MBBS, MS, FRCS, Consultant at Deenanath Mangeshkar Hospital, Pune, India
²MBBS, DORL, DNB ENT, Junior Consultant at Deenanath Mangeshkar Hospital, Pune, India
³MBBS, DNB ENT, Resident Doctor at Deenanath Mangeshkar Hospital, Pune, India

*Corresponding Author: Shradha Saindani, MBBS, DORL, DNB ENT, Junior Consultant at Deenanath Mangeshkar Hospital, Pune, India.

Received: November 18, 2025; Published: November 27, 2025

Abstract

Olfactory neuroblastoma (ONB) is a rare head and neck malignancy, accounting for 0.3% of upper aerodigestive tract malignancies and 3% - 6% of the sinonasal tract malignant tumours. It was first described in 1924 by Berger, Luc and Richard. It is a tumour of anterior skull base arising from the neuroepithelium of the olfactory cleft in the superior porion of the nasal cavity. ONB have an indolent course from a slow growing neoplasm to that of a highly aggressive and locally invasive neoplasm with a capacity of regional or distant metastases. Several treatment modalities have been described, given the rarity and recurrence pattern of the tumour, prospective treatment studies are absent. Craniofacial resection with adjuvant radiotherapy (RT) is the treatment of choice for respectable ONB tumours. Now a days in selected cases Endoscopic resection has gained popularity as they prevent facial incisions and craniotomy and is also oncologically sound . We present a case of ONB tumour in a 53 year old male. Patient present with a bleeding mass protruding out of the left nostril. Mass was diagnosed on Contrast enhanced computed tomography (CECT). Biopsy and debulking was planned under general anesthesia. Intraoperative samples were sent for frozen section sampling and procedure was completed once diagnosis was made. Immunohistochemical staining was done. Patient was further referred to Oncologist for Adjuvant Radiotherapy. This condition is quite rare and presentation is also late. So early diagnosis and prompt management improves the treatment outcome and prognosis of the patient.

Keywords:Esthesioneuroblastoma; Olfactory Neuroblastoma; Skull Base Tumour; Endoscopic Resection; Sinonasal Tumour

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Citation

Citation: Shradha Saindani., et al. “Esthesioneuroblastoma a Rare Tumour of the Sinonasal Vault: A Singular Case Narrative".Acta Scientific Otolaryngology 7.12 (2025): 27-31.

Copyright

Copyright: © 2025 Shradha Saindani., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.