Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Case Study Volume 7 Issue 5

A Case Series on Parathyroid Adenoma: A Medical Chameleon

Tanuj Madan1*, Gunjan Dwivedi2, Vikas Sharma3, Gurtej Singh4, Richa Ranjan5 and Parul Verma6

1Assistant Professor, Department of ENT, Command Hospital-Eastern Command, Kolkata, West Bengal, India
2Professor, Department of ENT, Command Hospital-Eastern Command, Kolkata, West Bengal, India
3Associate Professor, Department of ENT, Command Hospital-Eastern Command, Kolkata, West Bengal, India
4Assistant Professor, Medical Specialist and Endocrinologist, Department of Internal Medicine, Command Hospital- Eastern Command, Kolkata, West Bengal, India
5Professor, Department of ENT, Command Hospital-Eastern Command, Kolkata, West Bengal, India
6Consultant, Department of ENT, 153 General Hospital, Leh, India

*Corresponding Author: Tanuj Madan, Assistant Professor, Department of ENT, Command Hospital-Eastern Command, Kolkata, West Bengal, India.

Received: March 13, 2025; Published: April 21, 2025

Abstract

Parathyroid adenoma (PA) is a part of spectrum of parathyroid disease which also includes parathyroid hyperplasia and parathyroid carcinoma. More than 80 percent cases of parathyroid disease manifest as PA. Most patients of PA remain asymptomatic and get diagnosed incidentally. The present case series consists of case 1 who had psychiatric manifestations; case 2 who was being investigated for nephrocalcinosis and case 3 who was assessed for the complaint of backache. It is important to appreciate from our case series that all cases were completely staggered in their presentations and got referred to Otolaryngologist from very different specialties. The authors have compared this medical entity to a chameleon encountered in clinical medicine because of its myriad presentations. A high degree of suspicion and good clinical acumen are, therefore, mandatory to clinch the diagnosis. Precise surgical technique ensures achievement of normal health which is also depicted in our case series. The instant case report discusses the symptoms, investigative techniques: biochemical and imaging, surgical procedure and prospective clinical course of 3 cases of PA.

Keywords:Parathormone; Hypercalcemia; Primary Hyperparathyroidism; Parathyroidectomy; Nephrocalcinosis

References

  1. Bilezikian JP., et al. “Hyperparathyroidism”. The Lancet10116 (2018): 168-178.
  2. Mahmodlou R., et al. “Giant parathyroid adenoma: a case report”. Journal of Medical Case Reports1 (2022): 150.
  3. Mizamtsidi M., et al. “Diagnosis, management, histology and genetics of sporadic primary hyperparathyroidism: old knowledge with new tricks”. Endocrine Connections2 (2018): R56-68.
  4. Rutledge S., et al. “Acute presentation of a giant intrathyroidal parathyroid adenoma: a case report”. Journal of Medical Case Reports 10 (2016): 1-6.
  5. Cardoso L., et al. “Molecular genetics of syndromic and non‐syndromic forms of parathyroid carcinoma”. Human Mutation12 (2017): 1621-1648.
  6. Rao SD. “Epidemiology of parathyroid disorders”. Best Practice and Research Clinical Endocrinology and Metabolism6 (2018): 773-780.
  7. Walker MD and Silverberg SJ. “Primary hyperparathyroidism”. Nature Reviews Endocrinology2 (2018): 115-125.
  8. Martínez-Loya C., et al. “Bilateral giant parathyroid adenoma and hungry bone syndrome: a case report”. Journal of Medical Case Reports1 (2023): 373.
  9. Patel CN., et al. “Clinical utility of ultrasound and 99mTc sestamibi SPECT/CT for preoperative localization of parathyroid adenoma in patients with primary hyperparathyroidism”. Clinical Radiology 4 (2010): 278-287.
  10. Filser B., et al. “Predictors of adenoma size and location in primary hyperparathyroidism”. Langenbeck's Archives of Surgery 5 (2021): 1607-1614.

Citation

Citation: Tanuj Madan., et al. “A Case Series on Parathyroid Adenoma: A Medical Chameleon".Acta Scientific Otolaryngology 7.5 (2025): 26-31.

Copyright

Copyright: © 2025 Tanuj Madan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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