Ravinder Kaur, Shobha Mohindroo, Harjitpal Singh* and Rajinder Singh Yadav

Department of ENT, Dr RKGMC, Hamirpur, India

*Corresponding Author: Harjitpal Singh, Department of ENT, Dr RKGMC, Hamirpur, India.

Received: April 20, 2024; Published: May 17, 2024

Abstract

Background: There is limited data regarding the prevalence of thyroid disorders in women in India in general and of Himachal in particular, and this study assesses the thyroid disorder prevalence in women of Hamirpur district of Himachal, reporting in tertiary care Hospital.

Methods: All women who underwent blood sampling for estimation of thyroid function tests (TFTs) on their initial visit to the Hospital were included in the study.

Results: The study population included 1766 subjects from 18 to 50 years, and the mean age of study population was 27.56 years. They were divided in groups, 18 to 25 (40.2%), 26-35 (51.5%), 36-45 (7.5%) and >45 years (0.8%). Among these women, 1511 were referred by Anti Natal clinic and 255 were from rest of the Hospital. The mean age of ANC patients was 26.57 and of Non ANC was 33.41.

Conclusions: The thyroid function abnormalities are common in females and the prevalence increases with age. The prevalence rates of thyroid function disorders on the basis of uniform criteria for both pregnant and non-pregnant females were 7.18%, 11.41%, 23.66% and 42.86% in age groups of 18-25, 26-35, 36-45 and ≥ 45 years respectively. Overall prevalence of thyroid function disorders in females was 10.88% on screening and hypothyroidism (7.88%) being more common than hyperthyroidism (3%). The primary hypothyroidism (77.7%) was the commonest abnormality, followed by subclinical hypothyroidism (16.6%), secondary hyperthyroidism (5.7%) in the hypothyroid patients. While in hyperthyroid group of patients, the pattern was: subclinical (41.5%), followed by secondary (30.2%) and primary (30.2%).

Keywords: Prevalence; Thyroid Function Disorders; Hypothyroidism; Hyperthyroidism

References

1. Lakshminarayana Gopaliah R., et al. “Prevalence of thyroid dysfunction: Experience of a tertiary care centre in Kerala”. International Journal of Medical Research and Review 1 (2016): 12-18.
2. Yejin Kim., et al. “The Prevalence of Thyroid Dysfunction in Korean Women Undergoing Routine Health Screening: A Cross-Sectional Study”. Thyroid®7 (2022): 819-827.
3. Unnikrishnan AG., et al. “Prevalence of hypothyroidism in adults: An epidemiological study in eight cities of India”. Indian Journal of Endocrinology and Metabolism 17 (2013): 647-652.
4. Iodine Status Worldwide, WHO Global Database on Iodine Deficiency. Geneva: Department of Nutrition for Health and Development, WHO (2004).
5. Unnikrishnan AG., et al. “Prevalence of hypothyroidism in adults: An epidemiological study in eight cities of India”. Indian Journal of Endocrinology and Metabolism 17 (2013): 647-652.
6. Harach HR., et al. “Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis”. Acta Endocrinology (Copenh) 108 (1985): 55-60.
7. Marwaha RK., et al. “Status of thyroid function in Indian adults: Two decades after universal salt iodization”. Journal of the Association of Physicians of India 60 (2012): 32-36.
8. Usha Menon V., et al. “High prevalence of undetected thyroid disorders in an iodine sufficient adult south Indian population”. Journal of Indian Medical Association 107 (2009): 72-77.
9. Matyjaszek-Matuszek B., et al. “Diagnostic methods of TSH in thyroid screening tests”. Annals of Agricultural and Environmental Medicine 4 (2013): 731-735.
10. Gietka-Czernel M. “Postępy w laboratoryjnej diagnostyce czynności tarczycy”. Post Nauk Med. 2 (2008): 83-91.
11. Stagnaro-Green A., et al. “Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum”. Thyroid 21 (2011): 1081-1125.
12. Hhh Marwaha RK., et al. “Establishment of reference range for thyroid hormones in normal pregnant Indian women”. BJOG 115 (2008): 602-606.
13. Kalra S., et al. “Trimester-specific thyroid stimulating hormone: an Indian perspective”. Indian Journal of Endocrinology and Metabolism1 (2018): 1.
14. Kannan S., et al. “A systematic review on normative values of trimester-specific thyroid function tests in Indian women”. Indian Journal of Endocrinology and Metabolism 22 (2018): 7-12.
15. Ajmani SN., et al. “Prevalence of overt and subclinical thyroid dysfunction among pregnant women and its effect on maternal and fetal outcome”. The Journal of Obstetrics and Gynecology of India 2 (2014): 105.
16. Lara MC., et al. “Hypothyroidism screening during first trimester of pregnancy”. BMC Pregnancy Childbirth1 (2017): 438.
17. Haddow JE., et al. “Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child”. The New England Journal of Medicine 341 (1999): 549-555.
18. Alexander EK., et al. “Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum”. Thyroid 3 (2017): 315-389.
19. Iato"íccki V. “S"bcli⭲ical kQpotkQíoidism: a⭲ "pdatc roí píimaíQ caíc pkQsicia⭲s”. MaQo Cli⭲ Píoc. 4.1 (2009): 65-71.
20. Coopcí KS. “S"bcli⭲ical kQpotkQíoidism”. The New England Journal of Medicine4 (2001): 260-265.

Citation

Citation: Harjitpal Singh., et al. “The Prevalence of Thyroid Dysfunction in Women of Sub Himalayan Region Undergoing Routine Health Screening". Acta Scientific Otolaryngology 6.6 (2024): 04-10.

Copyright

Copyright: © 2024 Harjitpal Singh., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.