Rasha Nahan¹*, Dali Chandran¹, Honey Ashok¹, Reshma Ramanan¹ and Rajeswarie RT²

¹Department of E.N.T, Sakra World Hospital, Bangalore, India
²Department of Pathology, Sakra World Hospital, Bangalore, India

*Corresponding Author: Rasha Nahan, Department of E.N.T, Sakra World Hospital, Bangalore, India.

Received: February 03, 2024; Published: March 03, 2024

Abstract

Plasmacytomas are lymphoproliferative disorders characterized by monoclonal proliferation of plasma cells. Of these extramedullary plasmacytomas are rare tumors. They are mostly seen in the submucosa of the upper aerodigestive tract. Clinical manifestations vary depending on the location of the lesions. In the nasal cavity, it can cause nasal obstruction, anosmia/hyposmia, headache and epistaxis. The risk of conversion to multiple myeloma is 15%-20%. To rule out multiple myeloma, a complete systemic evaluation should be done in all patients with extramedullary plasmacytoma. Excision biopsy/IHC play an important role in differentiating and planning the management of these disorders. It is a highly radiosensitive tumor, so radiotherapy is the treatment of choice. We report a case of a 38 years old female presented to ENT department with nose block and diagnosed as extramedullary plasmacytoma without any systemic manifestation and no evidence of multiple myeloma, treated with surgery as sole modality of treatment and no recurrences on follow up to date, which makes this case different from others.
Even though radiotherapy is the treatment of choice, it can be treated with surgery alone if the lesion is small in size. Keeping the recurrence rates in mind, regular follow ups are required for early detection and treatment.

Keywords: Extramedullary Plasmacytoma; Multiple Myeloma; Immunohistochemistry; Serum Protein Electrophoresis; Serum Immunotyping

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Citation

Citation: Rasha Nahan., et al. “Multiple Nasal Swellings and An Unusual Diagnosis: Extramedullary Plasmacytoma".Acta Scientific Otolaryngology 6.4 (2024): 08-13.

Copyright

Copyright: © 2024 Rasha Nahan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.