Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Perspective Volume 5 Issue 4

A Spotlight on Recent Developments in Diagnosis and Treatment of Cholesteatoma

Santhosh Kumar Rajamani*

MAEER MIT Pune’s MIMER Medical College and DR. BSTR Hospital, Talegaon D, Pune, Maharashtra, India

*Corresponding Author: Santhosh Kumar Rajamani, MAEER MIT Pune’s MIMER Medical College and DR. BSTR Hospital, Talegaon D, Pune, Maharashtra, India.

Received: January 26, 2023; Published: March 31, 2023

Introduction

In 1838, when Johannes Müller first described Cholesteatoma, he thought that it was a tumour of the fatty tissue, (Latin: steat=fat). The reported annual incidence of Cholesteatoma worldwide is around 10 per 100,000. There have been reports of association between cholesteatoma and pediatric progressive sensorineural hearing loss [1]. Cholesteatoma ears show reduced microbial diversity with predominance gram positive cocci Staphylococcus aureus. Staph aureus cocci are associated with a progressive form of Cholesteatoma [2].

Keywords: Cholesteatoma; Surgery; Endoscopic; Diagnostic; Molecular Markers

References

  1. Tang Yiyang., et al. “Sensorineural Damage in Chronic Suppurative Otitis Media with and without Cholesteatoma: A Comparative Study”. Annals of Translational Medicine 14 (2022): 778.
  2. Frank Daniel N., et al. “Microbiota Associated With Cholesteatoma Tissue in Chronic Suppurative Otitis Media”. Frontiers in Cellular and Infection Microbiology 12 (2022): 746428.
  3. Alhelali Shaden., et al. “Secondary Acquired Cholesteatoma in Langerhans Cell Histiocytosis Patient”. Cureus12 (2022): e32173.
  4. Choi Yeonjoo., et al. “Endoscopic Ear Surgery for Congenital Cholesteatoma in Children”. The Journal of International Advanced Otology 3 (2022): 236-242.
  5. Rajamani Santhosh Kumar., et al. “Tympanometric Screening for Otitis Media of Paediatric Patients with Respiratory Tract Infection in Rural Setting a Prospective Observational Study”. Tropical Journal of Ophthalmology and Otolaryngology2 (2019): 100-108.
  6. Kim Hong Chan., et al. “Endoscopic Surgery of Congenital Cholesteatoma in the Anterior Epitympanic Recess: A Case Report of a Rare Location”. Ear, Nose, and Throat Journal10 (2022): 677-679.
  7. Shemesh Shay., et al. “Are Hounsfield Unit Measurements of Bony Absorption Changes in Cholesteatoma Helpful?” International Archives of Otorhinolaryngology3 (2022): e414-421.
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  9. Amoodi Hosam., et al. “Non-Echo Planar Diffusion-Weighted Imaging in the Detection of Recurrent or Residual Cholesteatoma: A Systematic Review and Meta-Analysis of Diagnostic Studies”. Cureus12 (2022): e32127.
  10. Baazil Adrianus H A., et al. “Identifying Epithelial Borders in Cholesteatoma Surgery Using Narrow Band Imaging”. European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS): Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery7 (2022): 3347-3354.
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  12. Cantone Elena., et al. “Endotyping of Cholesteatoma: Which Molecular Biomarkers? A Systematic Review”. Journal of Personalized Medicine8 (2022).
  13. Dambergs Kristaps., et al. “Remodeling Factors, Transcription Factors and Angiogenetic Factors in Cholesteatoma in Ontogenetic Aspect”. Iranian Journal of Otorhinolaryngology 121 (2022): 71-81.
  14. Early Samuel., et al. “A Fluorescent Photoimmunoconjugate for Imaging of Cholesteatoma”. Scientific Reports1 (2022): 19905.
  15. Liu Shuang., et al. “Generation of DNA-Aptamers Targeting Galectin-7 for the Identification of Cholesteatoma Residue”. Journal of Pharmacological Sciences3 (2022): 146-153.
  16. Kitaya Shiori., et al. “Immunohistochemical Localization of D-β-Aspartic Acid in Congenital and Acquired Middle Ear Cholesteatoma”. Laryngoscope Investigative Otolaryngology4 (2022): 1155-1163.
  17. Silva Mauricio Noschang Lopes., et al. “Endoscopic-Assisted Canal Wall-up Tympanomastoidectomy for Reduction of Residual Cholesteatoma”. International Archives of Otorhinolaryngology2 (2022): e260-264.
  18. Rajamani, Santhosh Kumar., et al. “Variations in the External Auditory Canal of 185 Adult Individuals: A Clinico-Morphological Study”. Variations in the External Auditory Canal of 185 Adult Individuals: A Clinico-Morphological Study7 (2013): 1-5.
  19. Richards Emma., et al. “Congenital Mastoid Cholesteatoma”. The Journal of International Advanced Otology4 (2022): 308-314.
  20. Zeng Nan., et al. “Transcanal Endoscopic Treatment for Congenital Middle Ear Cholesteatoma in Children”. Medicine29 (2022): e29631.
  21. Uz Zaman Sameeh., et al. “Temporal Bone Cholesteatoma: Typical Findings and Evaluation of Diagnostic Utility on High Resolution Computed Tomography”. Cureus3 (2022): e22730.

Citation

Citation: Santhosh Kumar Rajamani. “A Spotlight on Recent Developments in Diagnosis and Treatment of Cholesteatoma".Acta Scientific Otolaryngology 5.4 (2023): 56-59.

Copyright

Copyright: © 2023 Santhosh Kumar Rajamani. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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