Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Editorial Volume 4 Issue 9

Delayed-type Hypersensitivity Reaction to Facial Dermal Fillers After COVID-19 Vaccination

Poramate Pitak-Arnnop* and Andreas Neff

Department of Oral and Craniomaxillofacial Plastic Surgery, UKGM GmbH, University Hospital Marburg, Faculty of Medicine, Philipps-University of Marburg, Marburg, Germany

*Corresponding Author: Poramate Pitak-Arnnop, Department of Oral and Craniomaxillofacial Plastic Surgery, UKGM GmbH, University Hospital Marburg, Faculty of Medicine, Philipps-University of Marburg, Marburg, Germany.

Received: July 25, 2022; Published: August 01, 2022

Abstract

Over the past 1.5 years vaccination has become one of effective measures to combat the novel Coronavirus disease 2019 (COVID-19). Several adverse reactions arising from COVID-19 vaccines have been reported in the literature. These can be categorised into systemic and local adverse reactions – the former often presents with fever, fatigue, and headache, while the latter is frequently associated with pain, erythema, and swelling at the injection site. A recent meta-analysis demonstrated that different relative risks (RR) of systemic reactions depended upon the vaccine type, i.e., 1.13 (95% confidence interval [CI], 0.79 to 1.61), 1.53 (95% CI, 1.08 to 2.16), 1.58 (95% CI, 1.13 to 1.90), 0.72 (95% CI, 0.34 to 1.55), and 1.62 (95% CI, 1.39 to 1.89) for inactivated virus, mRNA, vector, DNA, and protein subunit vaccines, respectively. The RR of local adverse events following immunization with inactivated vaccine, mRNA vaccine, vector vaccine, DNA, and protein subunit vaccine was 2.18 (95% CI, 1.32 to 3.59), 4.96 (95% CI, 4.02 to 6.11), 1.48 (95% CI, 0.88 to 2.50), 1.04 (95% CI, 0.12 to 8.75), and 4.09 (95% CI, 2.63 to 6.35), respectively. However, the vaccine type was not a significant predictor of systemic and local adverse events. In other words, the vaccine safety is “relatively” comparable, in spite of the fact that mRNA vaccines tend to be related to higher adverse effects [1].

References

  1. Kouhpayeh H and Ansari H. “Adverse events following COVID-19 vaccination: A systematic review and meta-analysis”. International Immunopharmacology 109 (2022): 108906.
  2. Kalantari Y., et al. “A systematic review on COVID-19 vaccination and cosmetic filler reactions: A focus on case studies and original articles”. Journal of Cosmetic Dermatology (in press) (2022).
  3. Bachour Y., et al. “Late inflammatory reactions in patients with soft tissue fillers after SARS-CoV-2 infection and vaccination: A systematic review of the literature”. Journal of Cosmetic Dermatology 21 (2022): 1361-1368.
  4. Trinh LN., et al. “Delayed granulomas as a complication secondary to lip augmentation with dermal fillers: A systematic review”. Surgery Journal (New York, N. Y.) 8 (2022): e69-e79.
  5. Pitak-Arnnop P., et al. “A German AWMF’s S2e/realist synthesis and meta-narrative snapshot of craniomaxillofacial manifestations in COVID-19 patients: Rapid living update on 1 January 2021”. Journal of Stomatology, Oral and Maxillofacial Surgery 123 (2022): 64-73.
  6. Pitak-Arnnop P., et al. “What factors predict craniomandibular disorders in severe COVID-19 survivors after prolonged intubation?” Journal of Stomatology, Oral and Maxillofacial Surgery (in press) (2022).
  7. Wunsch A and Pitak-Arnnop P. “Strategic planning for maxillofacial trauma and head and neck cancers during COVID-19 pandemic- December 2020 updated from Germany”. American Journal of Otolaryngology 42 (2021): 102932.
  8. Pitak-Arnnop P., et al. “Prolonged viral shedding identified from external splints and intranasal packings in immediately cured COVID-19 patients with nasal fractures: A retrospective study”. Journal of Stomatology, Oral and Maxillofacial Surgery 123 (2022): 287-291.
  9. Pitak-Arnnop P., et al. “Inanimate surface contamination of SARS-CoV-2 during midfacial fracture repair in asymptomatic COVID-19 patients”. Journal of Stomatology, Oral and Maxillofacial Surgery (in press) (2022).
  10. Pitak-Arnnop P., et al. “Asymptomatic or mildly symptomatic COVID-19 patients with craniomaxillofacial injuries have an increase risk of surgical site infection”. British Journal of Oral and Maxillofacial Surgery (in press).
  11. Al-Moraissi EA., et al. “Can aerosols-generating dental, oral and maxillofacial, and orthopedic surgical procedures lead to disease transmission? An implication on the current COVID-19 pandemic”. Frontiers in Oral Health (in press) (2021).

Citation

Citation: Poramate Pitak-Arnnop and Andreas Neff. “Delayed-type Hypersensitivity Reaction to Facial Dermal Fillers After COVID-19 Vaccination".Acta Scientific Otolaryngology 4.9 (2022): 01-03.

Copyright

Copyright: © 2022 Poramate Pitak-Arnnop and Andreas Neff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

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