Very Enlarged Mandibular Osteosarcoma
Ahmet Baki*, Şahin Öğreden, Fatih Mert Doğukan and Semih Tekin
Department of Otolaryngology, Başakşehir Çam ve Sakura City Hospital, Turkey
*Corresponding Author: Ahmet Baki, Department of Otolaryngology, Başakşehir Çam ve Sakura City Hospital, Turkey.
February 09, 2022; Published: June 22, 2022
In this study, we aimed to present a huge mandibular tumor. In our study, we presented a 29-year-old patient with mandibular tumor. Osteosarcoma is the most common malignant tumor of bone that occurs mostly in the young age group. It is most common in the second decade. The most important areas of bone involvement are the metaphysis of the load-bearing joints. Osteosarcoma is rarely seen in the head and neck region. The most affected area in the head and neck region is the mandible. No matter how large jaw tumors are, they can be operated on with an experienced surgeon and adequate repair.
Keywords: Mandible; Osteosarcoma; Mesenchymal Tumors
- Pardhe ND., et al. “Giant Osteosarcoma of the Mandible”. Journal of College of Physicians and Surgeons Pakistan 9 (2017): S117-S119.
- Kyle S and Ettinger KA. “Sarcomas of the Jaws”. In: Fonseca RJ (ed) Oral and Maxillofacial Surgery, Volume 2, Third Edition. (2018): 643-669.
- Etanaiara Almeida., et al. “Chondroblastic osteosarcoma”. Journal of Oral and Maxillofacial Pathology3 (2014): 464-468.
- Bajpai M., et al. “Osteogenic Sarcoma of Mandible”. Journal of College of Physicians and Surgeons Pakistan3 (2017): S26-S27.
- “Osteosarcoma-Biology Behavior and Mechanism”. Edited by Kanya Honoki and Kurt Richard Weiss. Intech Open (2017).
- The WHO Classification of Tumours Editorial Board. WHO Classification of Tumours Soft Tissue and Bone Tumours, 5th Lyon: IARC Press (2020).
- Chaudhary M and Chaudhary SD. “Osteosarcoma of jaws”. Journal of Oral and Maxillofacial Pathology2 (2012): 233-238.
- Bajpai, M and Pardhe N. "Chondroblastic osteosarcoma: the wolf in sheep’s clothing". Cukurova Medical Journal 43 (2018) 761-762.
- George A and Mani V. “Gnathic osteosarcomas: review of literature and report of two cases in maxilla”. Journal of Oral and Maxillofacial Pathology2 (2011): 138-143.
- Paparella ML., et al. “Osteosarcoma of the jaw: an analysis of a series of 74 cases”. Histopathology 2013;63 (4): 551-557.
- Argon A., et al. “Osteosarcomas of jaw: experience of a single centre”. Journal of Plastic Surgery and Hand Surgery 1 (2015): 13-18.
- Bennett JH., et al. “Osteosarcoma of the jaws: a 30-year retrospective review”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 3 (2000): 323-332.
- Tabatabaei SH., et al. “Diagnostic challenges of low-grade central osteosarcoma of jaw: a literature review”. Journal of Dentistry2 (2015): 62-67.
- Yoshida A., et al. “MDM2 and CDK4 immunohistochemical coexpression in high-grade osteosarcoma: correlation with a dedifferentiated subtype”. The American Journal of Surgical Pathology 3 (2012): 423-431.
- Tabareau-Delalande F., et al. “Chromosome 12 long arm rearrangement covering MDM2 and RASAL1 is associated with aggressive craniofacial juvenile ossifying fibroma and extracranial psammomatoid fibro-osseous lesions”. Modern Pathology1 (2014): 48-56.
- Greanspan A., et al. “Differential Diagnosis in Orthopaedic Oncology”. Bone Forming (Osteogenic) Lesions. 2nd Philadelphia: Lippincott Williams and Wilkins (2007): 88-89.
- Greenspan A., et al. “Differential diagnosis of tumours and tumour-like lesions of bones and joints”. Lippincott Williams and Wilkins (1998).
- Murat Hız. “Osteosarcoma, malignant fibrous histiocytoma clinical radiology, pathology and treatment strategies”. TOTBİD Dergisi 13 (2014): 227-239.
- Picci P., et al. “Risk factors for local recurrence after limb-salvage surgery for highgrade osteosarcoma of the extremities”. Annals of Oncology9 (1997): 89903.
- Shah JP., et al. “Bone Tumors and Odontogenic Lesions”. Jatin Shah's Head And Neck Surgery And Oncology, Fıfth Edıtıon. (2020): 701 - 753.
- Gadwal SR., et al. “Primary osteosarcoma of the head and neck in pediatric patients: a clinicopathologic study of 22 cases with a review of the literature”. Cancer3 (2001): 598-605.
- The ESMO/European Sarcoma Network Working Group. “Bone sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up”. Annals of Oncology 23 (2012): vii100-vii109.
- Ketabchi A., et al. “Sarcomas of the head and neck: a 10-year retrospective of 25 patients to evaluate treatment modalities, function and survival”. British Journal of Oral and Maxillofacial Surgery 2 (2011): 116-120.
- Picci P., et al. “Relationship of chemotherapy-induced necrosis and surgical margins to local recurrence in osteosarcoma”. Journal of Clinical Oncology12 (1994): 2699-2705.
- Bertoni F., et al. “The Istituto Rizzoli-Beretta experience with osteosarcoma of the jaw”. Cancer7 (1991): 1555-1563.
- Mardinger O., et al. “Osteosarcoma of the jaw. The Chaim Sheba Medical Center experience”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 4 (2001): 445-451.
- Bacci G., et al. “Neoadjuvant chemotherapy in the treatment of osteosarcoma of the extremities: preliminary results in 131 cases treated preoperatively with methotrexate and cis-diamminoplatinum”. Italian Journal of Orthopaedics and Traumatology 1 (1988): 23-39.
- Thiele OC., et al. “Interdisciplinary combined treatment of craniofacial osteosarcoma with neoadjuvant and adjuvant chemotherapy and excision of the tumour: a retrospective study”. British Journal of Oral and Maxillofacial Surgery 7 (2008): 533-536.
- “Osteosarcoma of the Jaw: Classification, Diagnosis and Treatment”. Daris Ferrari, Laura Moneghini, Fabiana Allevi, Gaetano Bulfamante and Federico Biglioli. Additional information is available at the end of the chapter.