Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Research Article Volume 4 Issue 4

Patterns of Hearing Loss Among HIV Adult Patients Attending Clinic at Tertiary Hospital, Tanzania

Enica Richard Massawe1*, Ndeserua Moshi1, John Kimario2, Edwin Liyombo2 and Perfect Kishevo2

1Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania
2Muhimbili National Hospital, Tanzania

*Corresponding Author: Enica Richard Massawe, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania.

Received: January 26, 2022; Published: March 11, 2022

Abstract

Introduction: Hearing is a complex sense involving both the ear's ability to detect sounds and the brain's ability to interpret those sounds, including the sounds of speech. Hearing loss is the most frequent sensory deficit in human populations, affecting more than 250 million people in the world. Consequences of hearing impairment include inability to interpret speech sounds, often producing a reduced ability to communicate, economic and educational disadvantage, social isolation and stigmatization.

HIV/AIDS is among infectious diseases that has significant detrimental effects on the auditory system. As many as 75% of adults living with HIV are reported to experience at some point in time, auditory dysfunction secondary to HIV infection. The exact prevalence and mechanisms of auditory dysfunction remain unclear to date and poses challenges in the assessment, treatment and monitoring of these patients.

Objective: To determine the pattern of hearing loss among HIV/AIDS adult patients attending antiretroviral therapy(ART) clinic at Tertiary Hospital in Tanzania.

Study design: Descriptive cross-sectional study design based in hospital.

Methodology: A total of 371 HIV/AIDS adults patients attending ART clinic were enrolled. Patients were interviewed by the structured questionnaire followed by otoscopic examination and pure tone audiometry. The patient’s medical files were reviewed to get the recent CD4 count. All information obtained was entered in a computer and analysed using SPSS version 17 software. The Chi-square test for proportions were used to determine the differences among different groups

Results: The study included 371 HIV/AIDS adults patients 39.1% were males and 60.9% were females, 80.6% were on ART and 19.4% were not on ART. The prevalence of hearing loss was 33.2%. As age advances, there was an increase in hearing loss from 28.3%, 30.4% and 57.7% respectively which was statistically significant (P < 0.05). The study found that SNHL was high 19.1%, followed by conductive 11.6% and mixed hearing loss 2.4% (P < 0.05). Among the study population 32.3%, 30.5% and 37.2% were found to have hearing loss corresponding to CD4 <200, 200-499, and >500 respectively. These findings were not statistically significant (P > 0.05). There was an increase in the prevalence of SNHL15.5%, 18.1%, 22.5% and conductive hearing loss 10.8% 11.3%, 12.4% which was corresponding to increases in CD4 count CD4 <200, 200-499, and >500 respectively. Mild hearing loss was found to be 23.5% with decrease in percentage as severity of hearing loss increases. There was high prevalence of hearing loss in those not on ART 44.4% compared to 30.4% in those on ART. These findings were statistically significant (P < 0.05).

Conclusion: Hearing loss is of high prevalence in HIV patients. It is more prevalent in those not on ART as compared to those on ART. Further studies are important to see the correlation with these factors.

Keywords: Patterns of Hearing Loss; Human Immunodeficiency Virus; Adult Patients

References

  1. World Health Organization 9 (WHO). WHO case definition of HIV for surveillance and revised clinical staging and immunological classification of HIV related disease in adult and children (2007).
  2. De Carvalho Leal M., et al. “Influence of hypercalcemia in the formation of tympanosclerosis in rats”. Otology and Neurotology1 (2006): 27-32.
  3. Berlin CI. “Hair Cells and Hearing Aids”. Editor, Singular Publishing Group (1995).
  4. Steven D Rauch. “Idiopathic Sudden Sensorineural Hearing Loss”. The New England Journal of Medicine 359 (2008): 833-840.
  5. Report on the Global AIDS epidemic. Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO), Geneva- Swatziland (2008).
  6. Webber LM. “Pathogenesis of HIV infection and Diseases Progression”. In suvanepad D, W and Louw B (2010) HIV/AIDS related communication, Hearing and swallowing disorders (1st ed) San Diego Plural Publishing Inc (2010): 11-29.
  7. Bankaitis AE., et al. “Audiological changes associated with HIV infection”. Ear, Nose and Throat Journal5 (1995): 353-358.
  8. Bankaitis AE. “A Viewpoint: audiological changes attributable to HIV infection”. Audiology Today6 (1996): 14-16.
  9. Chandraselchar SS., et al. “Otologic and andiologic evaluation of human Immunodeficiency virus infected patients”. American Journal of Otolaryngology 21 (2000): 1-9.
  10. Sorensen P. “Manifestation of HIV in the Head and Neck”. Current Infections Disease Report (2010): 1-9.
  11. Williams B. “Ototoxicity may be associated with protease Inhibitor therapy”. Clinical Infections Diseases 33 (2001): 2100-2101.
  12. Dalton DS., et al. “The impact of HL on Quality of life in order Adults”. The Gerontologist5 (2003): 661-668.
  13. American Health Consultants. “AIDS patients often have hearing and speech problems”. AIDS Alert8 (1999).
  14. De-lange M. “A hearing profile of persons infected with Acquired Immunodefficiency Syndrome (AIDS) cited from van der”. Westhuizen., et al. 2012 (2007).
  15. Hoftmann C., et al. “HIV medicine”. 2007 (15th Ed) Paris, Cagliari Wappertal: Rlying Publisher (2009).
  16. Lin C., et al. JAMA Otolaryngology-- Head and Neck Surgery 139 (2013): 251-255.
  17. Matas CG., et al. “Audiological evaluation in children born to HIV-positive mother’s”. Revista Brasileira de Otorhinolaringologia 4 (2000): 317-324.
  18. Ichoza IC and Ross E. “Auditory function in a group of adult Infected with HIV/AIDs in Gaziteng South Africa”. South African Journal of Communication Disorders 49 (2002): 17-27.
  19. Cameron E. “The deafening silence of AIDS”. Health and Human Rights1 (2000): 7-24.
  20. Gold S and Tami T. “Otolaryngological manifestation in HIV/AIDS”. Seminars in Hearing2 (1998) 165-175.
  21. Ichoza Shangaze IC. “HIV/AIDs and auditory functioning in adults. The need for intensified research in the developing world”. African Journal of AIDS Research1 (2010): 1-9.
  22. Stearn N and Swanepoel DW. “Sensory and Neural Auditory Disorders Associated with HIV/AIDS”. (1st ed) San Diego 1 Plural Publishing Inc (2010): 243-288.
  23. Newton PJ. “The cause of HL in HIV infection”. Community Ear and Hearing Health 3 (2006): 11-14.
  24. Rinaldo A Brandwein., et al. “AIDS related ontological lesions”. Acta Otolaryngology 123 (2003): 672-674.
  25. Lalwani AK and Sooy CD. “Ontological and neurologic manifestations of acquired Immunodeficiency Syndrome”. The otolaryngological clinics of North America6 (1992): 1183-1198.
  26. Benson CA., et al. “Treating opportunistic infection among HIV infected adults and adolescents”. Recommendation from CDC, the National Institutes of Health, and the HIV Medicine Association/Infectious Diseases Society of America (2008): 1-135.
  27. Birchal MA., et al. “Auditory function in patients infected with the human immunodifficiency virus”. Clinical Otolaryngology and Allied Sciences2 (1992): 117-121.
  28. Salzer TA. “Neurotological manifestation of HIV infection”. Bobby R. Alford Department of otolaryngology Head and Neck Surgery Bayor College of Medicine. Grand round achieve (1994).
  29. Gurney TA and Murr AH. “Otolaryngologic manifestation of human Immunodeficiency Virus Infection”. Otolaryngologic Clinic North America 36 (2003): 607-624.
  30. Makau SM., et al. “The pattern of hearing disorders in HIV positive patients on anti-retrovirals at Kenyatta National Hospital”. East African Medical Journal 87 (2010): 425-429.
  31. Rey DL., et al. “Severe ototoxicity in a health care workers who received post exposure prophylaxis with stavudine, lamivudine and nevirapine after occupational exposure to HIV”. Clinical Infections Disease 34 (2002): 418-419.
  32. Simdon J., et al. “Ototoxicity associated with use of nucleoside analog reverse transcriptase inhibitors. A report of 3 possible cases and review of the literature”. HIV/AIDS 32 (2001): 1623-1627.
  33. Bankaitis AU and Kemp RJ. “Infection control in the Audiology Clinic”. (2nd Ed). Boulder, CO: Auban (2005).
  34. Bankaitis AE. “Infection control for communication, Hearing and Swallowing Disorders. In Swanepoel DW and Louw B. “HIV/AIDS related communication, hearing and swallowing disorders”. (1st ed). San Diego: Plural Publishing Inc. (2010): 63-96.

Citation

Citation: Enica Richard Massawe., et al. “Patterns of Hearing Loss Among HIV Adult Patients Attending Clinic at Tertiary Hospital, Tanzania".Acta Scientific Otolaryngology 4.4 (2022): 10-20.

Copyright

Copyright: © 2022 Enica Richard Massawe., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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