BV Manjula*

Department of Otolaryngology, India

*Corresponding Author: BV Manjula, Department of Otolaryngology, India.

Received: January 18, 2022; Published: February 28, 2022

What we know?

Rhino orbito cerebral Mucormycosis (ROCM) is a well known potentially lethal, fulminant fungal infection. It is caused by ubiquitous filamentous fungi belonging to the order of Mucorales. Predisposing factors as we know from pre COVID-19 era include a state of immunosuppresion, such as Diabetes mellitus (DM), Diabetic ketoacidosis (DKA) hematologic malignancy, hematopoietic stem cell transplantation, solid organ transplantation, immunosuppressive drugs, iron overload and chronic renal failure. Infection is the result of inhalation of sporangiospores followed by angio-invasion and thrombosis of blood vessel which leads to tissue necrosis. Specific reactions of fungal hyphae with endothelial cells result in systemic dissemination of the disease.

Citation

Citation: BV Manjula. “An Epidemic of Mucormycosis - Known to Unknown".Acta Scientific Otolaryngology 4.3 (2022): 40-41.

Copyright

Copyright: © 2022 BV Manjula. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.