José Luis Treviño-González¹, Victor Samual Zuñiga-Marquez², German A Soto-Galindo²*, José Rosmal Cortés-Ponce² and Luis Garza-Montelongo²

¹Chief of Otolaryngology - Head and Neck Surgery Department, University Hospital, Monterrey, Mexico
²Otolaryngology - Head and Neck Surgery Department, University Hospital, Monterrey, Mexico

*Corresponding Author: José Rosmal Cortés Ponce, Otolaryngology - Head and Neck Surgery Department, University Hospital, Monterrey, Mexico.

Received: January 24, 2022; Published: February 22, 2022

Abstract

Objective: To describe the sociodemographic, clinical, and surgical characteristics of pediatric patients who come for evaluation for laryngeal papillomatosis and associate them with their clinical outcomes.

Methods: Retrospective observational, longitudinal, and descriptive cohort. The medical records of patients who met the selection criteria were reviewed from January 2014 to August 2021.

Results: The average age at which these patients were diagnosed was 4.68 ± 3.26 years. From the diagnosis, it was found that the mean of interventions that they required later was 7.53 ± 8.28 throughout their lives and that the most predominant symptom in these patients was dysphonia, presenting in 14 (73.7%) subjects and that this same symptom it was found to be a factor associated with a greater number of interventions in these patients with a significance of p = .04. Unfortunately, the most frequent severities of dysplasia were moderate and severe with 8 (42%) and 7 (36%) patients respectively, which if we consider them together represent 78% of the studied population.

Conslusion: We fund that the median average survival in the three reoperation periods was approximately 6 months. The risk factor that had the greatest statistical significance based on its association with reinterventions was the age of onset of sexual life.

The mean age at which these patients were diagnosed was 4.68 years. The mean interventions required was 7.53 throughout their lives and that the most predominant symptom in these patients was dysphonia. The most frequent severities of dysplasia were moderate and severe. 

Keywords: Laryngeal Papillomatosis; Pediatric Otolaryngology; Human Papillomavirus; Recurrent Laryngeal Papillomatosis

References

1. Stachler RJ., et al. “Clinical Practice Guideline: Hoarseness (Dysphonia) (Update)”. Otolaryngology–Head and Neck Surgery (United States) 158 (2018): 1-42.
2. Stamataki Sofia., et al. “Juvenile Recurrent Respiratory Papillomatosis: Still A Mystery Disease With Difficutl Management”. Head and Neck2 (2007): 155-162.
3. Derkay CS. “Task Force on Recurrent Respiratory Papillomas: A Preliminary Report”. Archives of Otolaryngology - Head and Neck Surgery 12 (1995): 1386-1391.
4. Derkay CS and Bluher AE. “Update on Recurrent Respiratory Papillomatosis”. Otolaryngologic Clinics of North America 4 (2019): 669-679.
5. Hobbs CG., et al. “Human papillomavirus and head and neck cancer: a systematic review and meta-analysis”. Clinical Otolaryngology4 (2006): 259-266.
6. Isidro Soloaga. “Caracterización de Los Espacios Rurales en México a partir de Estadísticas Nacionales”. Publicación | Comisión Económica para América Latina y el Caribe (2021).
7. Wiatrak Brian J., et al. “Recurrent respiratory papillomatosis: a longitudinal study comparing severity associated with human papilloma viral types 6 and 11 and other risk factors in a large pediatric population”. The Laryngoscope11 (2004): 1-23.
8. Seedat R Y. “Juvenile-Onset Recurrent Respiratory Papillomatosis Diagnosis and Management - A Developing Country Review”. Pediatric Health, Medicine and Therapeutics 11 (2020): 39-46.
9. Verheijen Rene H M., et al. “EBCOG position statement: Gender neutral HPV vaccination for young adults”. European Journal of Obstetrics, Gynecology, and Reproductive Biology 246 (2020): 187-189.
10. Fortes Helena Ribeiro., et al. “Recurrent respiratory papillomatosis: A state-of-the-art review”. Respiratory Medicine 126 (2017): 116-121.
11. Niyibizi Joseph., et al. “Risk factors for the development and severity of juvenile-onset recurrent respiratory papillomatosis: a systematic review”. International Journal of Pediatric Otorhinolaryngology2 (2014): 186-197.

Citation

Citation: German A Soto-Galindo., et al. “Age of Sexual Life Onset as a Risk Factor for Reintervention in Pediatric Laryngeal Papillomatosis Patients".Acta Scientific Otolaryngology 4.3 (2022): 02-08.

Copyright

Copyright: © 2022 German A Soto-Galindo., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.