Lucas Daykson David Macedo de Oliveira¹*, Geraldo Druck Sant'anna², Davi Sandes Sobral³, Paulo Sergio Lins Perazzo³, Helissandro Andrade Coelho¹, Laise Araujo Aires dos Santos⁴, Maria Luiza Coelho de Sousa⁵ and Adrielle Almeida de Jesus⁵

¹Otorrinolaryngoloy, Santo Antonio Hospital, Brazil
²Otorrinolaryngoloy, Santa Casa de Porto Alegre, Brazil
³Otorrinolaryngoloy, Otorrinos, Feira de Santana, Brazil
⁴Otorrinolaryngoloy, Inooa - Salvador, Brazil
⁵Otorrinolaryngoloy, Universidade Tiredentes, Aracaju, Brazil

*Corresponding Author: Lucas Daykson David Macedo de Oliveira, Otorrinolaryngoloy, Santo Antonio Hospital, Brazil.

Received: October 04, 2021; Published: December 31, 2021

Abstract

Objective: To evaluate the association between Reinke’s Edema and central hypothyroidism in the population from the state of Bahia.

Methods: It was held a longitudinal observational study of the type of case control study. The case group was formed by patients with Reinke’s Edema, aged 40 years or more. Control group was made by female patients aged 40 years or more with other benign pathologies of the larynx. The diagnosis of central hypothyroidism is based on the biochemical analysis: the patients show low circulating concentrations of free T4, associated to normal to low serum levels of TSH.

Results: The study had 26 patients in the case group and 26 in the control group. Central hypothyroidism was found in 17,6% of the case group; as it had not been found in the control group, it was not possible to calculate the OR; however, data showed statistical significance (p 0,034).

Conclusion: When compared to the primary one, and, usually, it does not show goiter, and the TSH values, in most the cases, are not high; these characteristics seem to make it difficult the clinical suspicion, and it can cause controversies regarding the association between hypothyroidism and Reinke’s edema.

Keywords: Reinke’s Edema; Hypothyroidism; Central Hypothyroidism

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Citation

Citation: Lucas Daykson David Macedo de Oliveira., et al. “Case-control Study to Evaluate the Association Between Reinke’s Edema and Central Hypothyroidism".Acta Scientific Otolaryngology 4.1 (2022): 71-76.

Copyright

Copyright: © 2022 Lucas Daykson David Macedo de Oliveira., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.