Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Case Report Volume 3 Issue 10

Skin Metastasis from a Parotid Neoplasm

Eva Fuster Martín1*, Juan Sánchez Jiménez2 and Rocio Solórzano Mariscal3

1ENT Department, Hospital Regional Universitario de Málaga, Spain
2Maxillofacial Department, Hospital Universitario de Jaén, Spain
3Pathology Department, Hospital Universitario de Jerez, Cádiz, Spain

*Corresponding Author: Eva Fuster Martín, Sociedad Española de ORL (SEORL), European Academy of Otology and Neuro-Otology (EAONO), Málaga, Andalucía, Spain.

Received: August 18, 2021; Published: September 27, 2021

Abstract

Salivary duct carcinomas are rare tumors known for their predominant location in the parotid gland, its aggressive behavior and high rate of recurrence. It resembles pathologically and immunophenotypically to high-grade ductal breast adenocarcinoma. This report presents an additional case of cutaneous metastasis from a salivary duct carcinoma of parotid gland. We have found thirteen more cases in the literature and we have noticed that every case follow a different treatment scheme. The limited number of cases reported in the literature make difficult to design a treatment protocol. However, new emerging clinical studies are comparing gene and protein expression levels between salivary duct carcinoma and breast carcinoma to identify future targeted therapy.

Keywords: Adenocarcinoma; Parotid Neoplasms; Neoplasm Metastasis; Skin Neoplasms

References

  1. Kleinsasser O., et al. “[Salivary duct carcinoma. A group of salivary gland tumors analogous to mammary duct carcinoma]”. Archiv fur Klinische Und Experimentelle Ohren- Nasen- Und Kehlkopfheilkund1 (1968): 100-105.
  2. Xie S., et al. “Salivary duct carcinoma of the parotid gland: A case report and review of the literature”. Oncology Letters1 (2015): 371-374.
  3. Campos-Gómez S., et al. “Case report: anti-hormonal therapy in the treatment of ductal carcinoma of the parotid gland”. BMC Cancer 14 (2014): 701.
  4. Jaehne M., et al. “Clinical and immunohistologic typing of salivary duct carcinoma: a report of 50 cases”. Cancer12 (2005): 2526-2533.
  5. Cohen PR., et al. “The “shield sign” in two men with metastatic salivary duct carcinoma to the skin: cutaneous metastases presenting as carcinoma hemorrhagiectoides”. The Journal of Clinical and Aesthetic Dermatology9 (2012): 27-36.
  6. Spencer PS and Helm TN. “Skin metastases in cancer patients”. Cutis 2 (1987): 119-121.
  7. Brownstein MH and Helwig EB. “Metastatic tumors of the skin”. Cancer5 (1972): 1298-1307.
  8. Schwartz RA., et al. “Inflammatory metastatic carcinoma of the parotid”. Archives of Dermatological6 (1984): 796-797.
  9. Dequanter D., et al. “Skin metastases from a head and neck carcinoma: a prognostic factor?” B-ENT3 (2005): 113-115.
  10. Dalin MG., et al. “Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer”. American Association for Cancer Research18 (2016): 4623-4633.
  11. Al-Qahtani KH., et al. “Clinicopathological features and treatment outcomes of the rare, salivary duct carcinoma of parotid gland”. Journal of Otolaryngology-Head and Neck Surgery1 (2016): 32.
  12. “Salivary duct carcinoma metastatic to the skin”. Journal of the American Academy of Dermatology5 (2016): AB71.
  13. Ha*iji J., et al. “A rare cutaneous presentation of metastatic parotid adenocarcinoma”. Australasian Journal of Dermatology2 (2013): e40-42.
  14. Pollock JL and Catalano E. “Metastatic ductal carcinoma of the parotid gland in a patient with sarcoidosis”. Archives of Dermatological9 (1979): 1098-1099.
  15. Tok J., et al. “Cutaneous metastasis from a parotid adenocarcinoma. Report of a case with immunohistochemical findings and review of the literature”. The American Journal of Dermatopathology3 (1995): 303-306.
  16. Zanca A., et al. “Telangiectatic metastasis from ductal carcinoma of the parotid gland”. Journal of the American Academy of Dermatology1 (1993): 113-114.
  17. 2011.36.pdf (2011).
  18. Aloi PG., et al. “[Cutaneous metastasis with an inflammatory aspect in parotid carcinoma]”. G Ital Dermatol E Venereol Organo Uff Soc Ital Dermatol E Sifilogr.4 (1987): 193-195.
  19. Plantin P., et al. “[Cutaneous extension of parotid carcinoma]”. Annales de Dermatologie et de Vénéréologie8 (1994): 571-573.
  20. Eroglu A., et al. “Basal cell adenocarcinoma of the parotid gland with rare scalp metastasis: a case report”. Turkish Neurosurgery1 (2015): 177-179.

Citation

Citation: Eva Fuster Martín., et al. “Skin Metastasis from a Parotid Neoplasm".Acta Scientific Otolaryngology 3.10 (2020): 80-85.

Copyright

Copyright: © 2020 Eva Fuster Martín., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Impact Factor0.871

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