Saud Ahmed¹, S Sharfa Afreen²* and Mohammed Zuhaib³

¹Chief Consultant - ENT, Head and Neck Services, Primecare Hospital, Bangalore, India
²Junior Consultant ENT, Head and Neck Services, Primecare Hospital, Bangalore, India
³Consultant OMFS, Head and Neck Oncology, Primecare Hospital, Bangalore, India

*Corresponding Author: S Sharfa Afreen, Junior Consultant ENT, Head and Neck Services, Primecare Hospital, Bangalore, India.

Received: April 12, 2021; Published: July 14, 2021

Abstract

The Maxillofacial region is a highly complex structure of human body composed of multiple tissue types including teeth, salivary glands, sense organs, lining tissues and facial bones. All of which undergo significant loss in Trauma, pathology or developmental deformities. Moreover, this requires replacement with grafts and flaps from the donor sites resulting in morbidities. This poses a difficult challenge to the maxillofacial surgeons as well as increase the suffering to the patient. This is where idea behind tissue engineering steps in. Tissue engineering is based on harvesting of stem cells which have the ability to form an organ. This article reviews the principles of tissue engineering and its various applications in oral and maxillofacial surgery.

Keywords: Maxillofacial Region; Stem Cell Therapy; Maxillofacial Reconstruction

References

1. Srisuwan T., et al. “Molecular aspects of tissue engineering in the dental field”. Periodontology 41 (2000): 88-108.
2. Wang KH., et al. “Modern concepts in mandibular reconstruction in oral and oropharyngeal cancer”. Current Opinion in Otolaryngology and Head and Neck Surgery2 (2011): 119-124.
3. Susarla SM., et al. “Craniomaxillofacial reconstruction using allotransplantation and tissue engineering: Challenges, opportunities, and potential synergy”. Annals of Plastic Surgery6 (2011): 655-661.
4. Meyer U. “The history of tissue engineering and regenerative medicine in perspective”. In: Meyer U, Meyer T, Handschel J, Wiesmann HP, editors. Fundamentals of tissue engineering and regenerative medicine. Springer-Verlag Berlin Heidelberg (2009): 5.
5. Ward BB., et al. “Bioengineering strategies for regeneration of craniofacial bone: A review of emerging technologies”. Oral Diseases8 (2010): 709-716.
6. Conrad C and Huss R. “Adult stem cell lines in regenerative medicine and reconstructive surgery”. Journal of Surgical Research2 (2005): 201-208.
7. Patil AS., et al. “Tissue engineering of craniofacial tissues – A review”. Journal of Tissue Engineering and Regenerative Medicine 2 (2013): 6.

Citation

Citation: S Sharfa Afreen., et al. “Stem Cell Therapy in Maxillofacial Reconstruction".Acta Scientific Otolaryngology 3.8 (2020): 63-64.

Copyright

Copyright: © 2020 S Sharfa Afreen., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.