Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Mini Review Volume 3 Issue 8

Stem Cell Therapy in Maxillofacial Reconstruction

Saud Ahmed1, S Sharfa Afreen2* and Mohammed Zuhaib3

1Chief Consultant - ENT, Head and Neck Services, Primecare Hospital, Bangalore, India
2Junior Consultant ENT, Head and Neck Services, Primecare Hospital, Bangalore, India
3Consultant OMFS, Head and Neck Oncology, Primecare Hospital, Bangalore, India

*Corresponding Author: S Sharfa Afreen, Junior Consultant ENT, Head and Neck Services, Primecare Hospital, Bangalore, India.

Received: April 12, 2021; Published: July 14, 2021

Abstract

The Maxillofacial region is a highly complex structure of human body composed of multiple tissue types including teeth, salivary glands, sense organs, lining tissues and facial bones. All of which undergo significant loss in Trauma, pathology or developmental deformities. Moreover, this requires replacement with grafts and flaps from the donor sites resulting in morbidities. This poses a difficult challenge to the maxillofacial surgeons as well as increase the suffering to the patient. This is where idea behind tissue engineering steps in. Tissue engineering is based on harvesting of stem cells which have the ability to form an organ. This article reviews the principles of tissue engineering and its various applications in oral and maxillofacial surgery.

Keywords: Maxillofacial Region; Stem Cell Therapy; Maxillofacial Reconstruction

References

  1. Srisuwan T., et al. “Molecular aspects of tissue engineering in the dental field”. Periodontology 41 (2000): 88-108.
  2. Wang KH., et al. “Modern concepts in mandibular reconstruction in oral and oropharyngeal cancer”. Current Opinion in Otolaryngology and Head and Neck Surgery2 (2011): 119-124.
  3. Susarla SM., et al. “Craniomaxillofacial reconstruction using allotransplantation and tissue engineering: Challenges, opportunities, and potential synergy”. Annals of Plastic Surgery6 (2011): 655-661.
  4. Meyer U. “The history of tissue engineering and regenerative medicine in perspective”. In: Meyer U, Meyer T, Handschel J, Wiesmann HP, editors. Fundamentals of tissue engineering and regenerative medicine. Springer-Verlag Berlin Heidelberg (2009): 5.
  5. Ward BB., et al. “Bioengineering strategies for regeneration of craniofacial bone: A review of emerging technologies”. Oral Diseases8 (2010): 709-716.
  6. Conrad C and Huss R. “Adult stem cell lines in regenerative medicine and reconstructive surgery”. Journal of Surgical Research2 (2005): 201-208.
  7. Patil AS., et al. “Tissue engineering of craniofacial tissues – A review”. Journal of Tissue Engineering and Regenerative Medicine 2 (2013): 6.

Citation

Citation: S Sharfa Afreen., et al. “Stem Cell Therapy in Maxillofacial Reconstruction".Acta Scientific Otolaryngology 3.8 (2020): 63-64.

Copyright

Copyright: © 2020 S Sharfa Afreen., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

Indexed In








News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is June 30, 2022.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US