Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Research Article Volume 3 Issue 8

Managing Odontogenic Keratocysts: An Enygma? Considerations to Choose the Correct Approach

Lopez Jondalys1, Solano Nicolás2, Rivera Ejusmar1, Castrillo Ariamay3* and Chirinos Yenielis3

1Oral Surgery Post-graduated Program, School of Dentistry, Universidad del Zulia, Venezuela
2Assistant Professor, Oral Surgery Post-graduated Program, School of Dentistry, Universidad del Zulia, Venezuela
3Resident, Oral Surgery Post-graduated Program, School of Dentistry, Universidad del Zulia, Venezuela

*Corresponding Author: Castrillo Ariamay, Resident, Department of Oral and Maxillofacial Surgery. Dentistry Service. University Hospital of Maracaibo, Zulia, Venezuela.

Received: June 08, 2021; Published: June 26, 2021

Abstract

Purpose: The aim of this study is to propose a protocol for the appropriate management and treatment of odontogenic keratocysts.

Materials and Methods: A longitudinal descriptive study on patients with odontogenic keratocysts surgically treated in the Oral and Maxillofacial Surgery Unit of the University Hospital of Maracaibo, Venezuela during the period between January 2015 and January 2020. Using a management algorithm, the treatment modality for each patient was described based on clinical, radiographic characteristics and biological behavior of the lesion.

Results: 10 patients were included in the study. The average age was 44.7 ± 21 years and 60% of the patients were female. All lesions were located in the mandible, 2 of the lesions had radiographic evidence of cortical perforation. The average radiographic diameter of the lesions was 6.3 ± 2.2 cm. Regarding the surgical variables, 7 patients received decompression + residual cystectomy, 1 patient enucleation and curettage and 2 patients received marginal or en-bloc resection.

Conclusion: It is necessary to unify different variables, like biological behavior and surgical and radiographic characteristics, since they are widely scattered in the literature and thus being able to protocolize the management of these lesions to obtain better results and decrease the recurrence rate.

Keywords: Odontogenic Keratocyst; Decompression; Enucleation; Resection; Recurrence

References

  1. Vallejo K., et al. “Conservative management of odontogenic keratocyst with long-term 5-year follow-up: Case report and literature review”. International Journal of Surgery Case Reports 66 (2020): 8-15.
  2. M Pogrel. “The keratocystic odontogenic tumour (KCOT)- An odyssey”. International Journal of Oral and Maxillofacial Surgery 44 (2015): 1565-1568.
  3. Philipsen HP. “Om keratocyster (kolesteatom) I kaeberne”. Tandlaege Bladet 60 (1956): 963-981.
  4. Kolokythas A., et al. “Odontogenic Keratocyst: To Decompress or Not to Decompress? A Comparative Study of Decompression and Enucleation Versus Resection/Peripheral Ostectomy”. Journal of Oral and Maxillofacial Surgery 65 (2007): 640-644.
  5. Sigua-Rodriguez E., et al. “Is Surgical Treatment Based on a 1-Step or 2-Step Protocol Effective in Managing the Odontogenic Keratocyst?” Journal of Oral and Maxillofacial Surgery 77 (2019): 1210-1217.
  6. Giuliani M., et al. “Conservative Management of a Large Odontogenic Keratocyst: Report of a Case and Review of the Literature”. Journal of Oral and Maxillofacial Surgery 64 (2016): 308-316.
  7. B Kinard., et al. “For Treatment of Odontogenic Keratocysts, Is Enucleation, When Compared to Decompression, a Less Complex Management Protocol”. Journal of Oral and Maxillofacial Surgery 73 (2015): 641-648.
  8. Bell R and Dierks E. “Treatment options for the recurrent odontogenic keratocyst”. Oral and Maxillofacial Surgery Clinics of North America 15 (2003): 429-446.
  9. Farias J., et al. “Clinicopathologic features associated with recurrence of the odontogenic keratocyst: a cohort retrospective analysis”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 121 (2016): 629-635.
  10. Y Anavi., et al. “Decompression of odontogenic cystic lesions: clinical long-term study of 73 cases”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 112 (2011): 164-169.
  11. J Madras and H Lapointe. “Keratocytic Odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour”. Journal of the Canadian Dental Association 74 (2008): 165.
  12. E Al-Moraissi., et al. “Does the excision of overlying oral mucosa reduce the recurrence rate in the treatment of the keratocystic odontogenic tumor? A systematic review and metaanalysis (2016).
  13. N Ledderhof., et al. “Topical 5-Fluorouracil is a Novel Targeted Therapy for the Keratocystic Odontogenic Tumor”. Journal of Oral and Maxillofacial Surgery 75 (2017): 514-524.
  14. F Sharif., et al. “Interventions for the treatment of keratocystic odontogenic tumors”. Cochrane Database of Systematic Reviews 8 (2010): 64-84.
  15. N., et al. “The Changing landscape in treatment of cystic lesions of the jaws”. Journal of International Society of Preventive and Community Dentistry 9 (2019): 328-337.
  16. Kahraman D., et al. “A series of 240 odontogenic keratocysts: Should we continue to use the terminology of keratocystic odontogenic tumor for the solid variant of odontogenic keratocyst?” Journal of Cranio-Maxillofacial Surgery 46 (2018): 942-946.
  17. B Kinard., et al. “How well do we manage the odontogenic keratocyst? A multicenter study”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 127 (2019): 282- 288.
  18. V Varinauskas., et al. “Analysis of odontogenic cysts of the jaws”. Medicina 42 (2006): 201-207.
  19. N Nakamura., et al. “Marsupialization for odontogenic keratocysts: long-term follow-up analysis of the effects and changes in growth characteristics”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 94 (2002): 543-553.
  20. P Marker., et al. “Treatment of large odontogenic keratocysts by decompression and later cystectomy: a long-term follow-up and a histologic study of 23 cases”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 82 (1996): 122-131.
  21. Khan A., et al. “Management of an extensive odontogenic keratocyst A rare case report with 10-year follow-up”. Medicine 98 (2019): 51.
  22. H Lee., et al. “Investigation of Postoperative Complications of Intrabony Cystic Lesions in the Oral and Maxillofacial Region”. Journal of Cranio-Maxillo-Facial Surgery 77 (2019): 1823-1831.
  23. E Moraissi., et al. “What surgical treatment has the lowest recurrence rate following the management of keratocystic odontogenic tumor?: A large systematic review and meta-analysis”. Journal of Cranio-Maxillo-Facial Surgery 45 (2017): 131-144.
  24. B Chrcanovic and R Gomez. “Recurrence probability for keratocystic odontogenic tumors: An analysis of 6427 cases”. Journal of Cranio-Maxillo-Facial Surgery 45 (2017): 244-251.

Citation

Citation: Castrillo Ariamay., et al. “Managing Odontogenic Keratocysts: An Enygma? Considerations to Choose the Correct Approach".Acta Scientific Otolaryngology 3.8 (2020): 75-81.

Copyright

Copyright: © 2020 Castrillo Ariamay., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

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