Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Mini Review Volume 3 Issue 11

Current Considerations for Injectable Nasal Fillers

Joanna Kam and Oren Friedman*

Department of Otorhinolaryngology, Division of Facial Plastic Surgery, University of Pennsylvania Health System, USA

*Corresponding Author: Oren Friedman, Director Facial Plastic Surgery, Department of Otorhinolaryngology, University of Pennsylvania Health System, Philadelphia, PA, USA.

Received: April 26, 2021; Published: November 29, 2021


  Injectable soft tissue filler procedures continue to grow in popularity as a minimally invasive option to address facial volume loss, rhytids and contour deformities. Nonsurgical, injectable, or liquid rhinoplasty refers to the use of injectable filler to augment limited areas of the nose, improving nasal appearance or function. Hyaluronic acid and calcium hydroxylapatite are the most commonly used nasal filler materials, given their rheologic properties, lifting capacity, biocompatibility, and longevity. Despite a growing body of literature describing how to safely perform nonsurgical rhinoplasty, complications including vascular occlusion, skin necrosis and blindness have been well described. This article reviews the indications for nonsurgical rhinoplasty, considerations when choosing a filler product, pertinent anatomy, pearls for injection technique and provides an overview of known complications.

Keywords: Injectable Filler; Soft Tissue Filler; Non-Surgical Rhinoplasty; Liquid Rhinoplasty; Hyaluronic Acid


  1. Kontis Theda C and Alexander Rivkin. “The history of injectable facial fillers”. Facial Plastic Surgery: FPS 2 (2009): 67-72.
  2. Greco Timothy M., et al. “Injectable fillers for volume replacement in the aging face”. Facial Plastic Surgery: FPS1 (2012): 8-20.
  3. American Society of Plastic Surgeons. “2000/2008/2009 National Plastic Surgery Statistics Cosmetic and Reconstructive Procedure Trends” (2009).
  4. American Society of Plastic Surgeons. “Plastic Surgery Statistics Report 2019”.
  5. Han Seung-Kyu., et al. “Augmentation rhinoplasty using injectable tissue-engineered soft tissue: a pilot study”. Annals of Plastic Surgery3 (2006): 251-255.
  6. Harb Ayad and Colin T Brewster. “The Nonsurgical Rhinoplasty: A Retrospective Review of 5000 Treatments”. Plastic and Reconstructive Surgery3 (2020): 661-667.
  7. Rivkin Alexander and Soliemanzadeh Peyman. “Nonsurgical injection rhinoplasty with calcium hydroxylapatite in a carrier gel (radiesse): A 4-year, retrospective, clinical review”. Cosmetic Dermatology12 (2009): 619-624.
  8. Kontis Theda C. “The Art of Camouflage: When Can a Revision Rhinoplasty Be Nonsurgical?”. Facial Plastic Surgery: FPS3 (2018): 270-277.
  9. Kontis Theda C. “Nonsurgical Rhinoplasty”. JAMA Facial Plastic Surgery5 (2017): 430-431.
  10. Johnson Owen N and Theda C Kontis. “Nonsurgical Rhinoplasty”. Facial Plastic Surgery: FPS5 (2016): 500-506.
  11. Nyte Christopher P. “Spreader graft injection with calcium hydroxylapatite: a nonsurgical technique for internal nasal valve collapse”. The Laryngoscope7 (2006): 1291-1292.
  12. Mehta Umang and Zachary Fridirici. “Advanced Techniques in Nonsurgical Rhinoplasty”. Facial Plastic Surgery Clinics of North America3 (2019): 355-365.
  13. Humphrey Clinton D., et al. “Soft tissue fillers in the nose”. Aesthetic Surgery Journal6 (2009): 477-484.
  14. Park Michelle E., et al. “Silicone Granulomas, a Growing Problem?”. The Journal of Clinical and Aesthetic Dermatology5 (2016): 48-51.
  15. Lee Jeong Min and Yu Jin Kim. “Foreign body granulomas after the use of dermal fillers: pathophysiology, clinical appearance, histologic features, and treatment”. Archives of Plastic Surgery2 (2015): 232-239.
  16. Toriumi D M., et al. “Vascular anatomy of the nose and the external rhinoplasty approach”. Archives of Otolaryngology--Head and Neck Surgery 122.1 (1996): 24-34.
  17. Rohrich RJ., et al. “Nasal tip blood supply: an anatomic study validating the safety of the transcolumellar incision in rhinoplasty”. Plastic and Reconstructive Surgery5 (1995): 795-799.
  18. Lazzeri Davide., et al. “Blindness following cosmetic injections of the face”. Plastic and Reconstructive Surgery4 (2012): 995-1012.
  19. Na Young-Cheon., et al. “Epinephrine Vasoconstriction Effect Time in the Scalp Differs According to Injection Site and Concentration”. Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery9 (2016): 1054-1060.
  20. Williams Lauren., et al. “Nonsurgical Rhinoplasty: A Systematic Review of Technique, Outcomes, and Complications”. Plastic and Reconstructive Surgery1 (2020): 41-51.
  21. De Victor Sam., et al. “Complications Secondary to Nonsurgical Rhinoplasty: A Systematic Review and Meta-analysis”. Otolaryngology--Head and Neck Surgery: Official Journal of American Academy of Otolaryngology-Head and Neck Surgery (2021).
  22. Rivkin Alexander. “Nonsurgical Rhinoplasty Using Injectable Fillers: A Safety Review of 2488 Procedures”. Facial Plastic Surgery and Aesthetic Medicine1 (2021): 6-11.
  23. King Martyn., et al. “Management of a Vascular Occlusion Associated with Cosmetic Injections”. The Journal of Clinical and Aesthetic Dermatology1 (2020): E53-E58.
  24. Urdiales-Gálvez Fernando., et al. “Treatment of Soft Tissue Filler Complications: Expert Consensus Recommendations”. Aesthetic Plastic Surgery2 (2018): 498-510.
  25. Hayreh Sohan Singh and M Bridget Zimmerman. “Central retinal artery occlusion: visual outcome”. American Journal of Ophthalmology 140.3 (2005): 376-391.
  26. Van Loghem Jani., et al. “Managing intravascular complications following treatment with calcium hydroxylapatite: An expert consensus”. Journal of Cosmetic Dermatology 11 (2020): 2845-2858.


Citation: Joanna Kam and Oren Friedman. “Current Considerations for Injectable Nasal Fillers".Acta Scientific Otolaryngology 3.11 (2020): 107-112.


Copyright: © 2020 Joanna Kam and Oren Friedman. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is June 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US