Department of Biochemistry, Indira Gandhi Institute of Medical Sciences, Patna, India
*Corresponding Author: Baban Kumar, Department of Biochemistry, Indira Gandhi Institute of Medical Sciences, Patna, India.
Received: February 19, 2021; Published: May 11, 2021
Background: The study aimed to assess the different manifestations of MMP among patients diagnosed as MMP.
Methodology: The study was conducted as a cross sectional study at PMCH, Patna for a period of 3 years on 30 patients diagnosed as a case of MMP in the departments of Otorhinolaryngology, dermatology and ophthalmology. Detailed history regarding clinical features, mode of presentation, and duration of symptoms was obtained and entered in questionnaire. Statistical analysis- Data was compiled using Ms Excel and analysed using IBM SPSS 20. Categorical data was expressed as frequency and percentage.
Results: Majority of patients with MMP belonged to 61 to 80 years of age (83.3%) and majority of cases were females. The most common site of involvement was oral mucosa (96.7%), followed by ocular conjunctiva in 63.3% and laryngeal mucosa (46.7%). About 55.8% patients with oral lesions presented with oral ulceration and about 47.4% cases with ocular lesions presented with non-specific conjunctivitis. In cases with laryngeal involvement, 28.6% cases presented with laryngeal stenosis with breathing difficulty. Nasal mucosal erosions, localized erythematous plaque, dysphagia and odynophagia were predominant manifestations in cases with nasal, skin, pharynx and oesophageal involvement respectively.
Conclusion: Mucous membrane pemphigoid is a rare disorder which most commonly involve oral mucosa. However, ocular, nasopharynx, larynx, oesophagus involvement can also be observed. Depending upon site of involvement, patients may present with varied manifestations such as oral erosions and ulcers, desquamative gingivitis in case of oral lesions, cicatrizing conjunctivitis in case of ocular involvement.
Keywords: Mucous Membrane Pemphigoid; Oral; Ocular; Pseudo Membrane; Airway
Citation: Baban Kumar. “Mucous Membrane Pemphigoid with Different Manifestations- A Cross Sectional Study"..Acta Scientific Otolaryngology 3.6 (2020): 40-43.
Copyright: © 2020 Baban Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.