Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Research Article Volume 3 Issue 2

Treatment of Sensorineural Hearing Loss in Children: Platelet Rich Plasma

Brajpal Singh Tyagi*

Department of ENT, Columbia Asia Hospital Ghaziabad, CEO Harsh ENT Hospital, Centre for Deafness, ABR Health Care Solutions Limited, India

*Corresponding Author: Brajpal Singh Tyagi, Department of ENT, Columbia Asia Hospital Ghaziabad, CEO Harsh ENT Hospital, Centre for Deafness, ABR Health Care Solutions Limited, India

Received: December 14, 2020; Published: January 23, 2021



Introduction: Hearing loss is one of the common disabilities in India. The prevalence of this disability is higher in children. The children with sensorineural hearing loss is very common which requires the safe, clinically effective and cost effective method of treatment.

Methods: The platelet rich plasma (PRP) was instilled in 24 children od age less than 10 years and the hearing improvement was assessed by the audiogram through BERA or PTA.

Results: It was found that 87% patients had bilateral impairment, and maximum patients were with moderate hearing impairment. The rate of improvement was found to be 99% except one patient who had no improvement in the left ear post PRP.

Conclusion: In our study, the patients with moderate to profound sensorineural hearing loss were found to have improved hearing levels after treatment with PRP which directly enhanced their speech discrimination levels. Further studies with bigger sample size are needed to establish this method as new doorway for improving the childhood hearing.

Keywords: Sensorineural Hearing Loss; PRP; Children with Hearing Loss; BERA



  1. Sulabha M., et al. “Rehabilitation of hearing impaired children in India – An update”. Otolaryngology 1 (2013): 1-12.
  2. Varshney S. “Deafness in India”. Indian Journal of Otology2 (2016): 73-76.
  3. Davey S., et al. “Impact of indian public health standards for rural health care facilities on national programme for control of deafness in India: The results of a cohort study”. Journal of Family Medicine and Primary Care 4 (2018): 780-786.
  4. MA Bashar Nk., et al. “Epidemiology of Childhood and Adult Deafness and the strategies for Prevention and Control in India”. Annals of Otolaryngology and Rhinology6 (2017): 1185.
  5. Barot DTaD. “Brainstem-evoked response audiometry in pediatric age group”. Indian Journal of Otology 4 (2018): 246-251.
  6. Da-An Huh Y-HC., et al. “Comparison of pure-tone average methods for estimation of hearing loss caused by environmental exposure to lead and cadmium: Does the pure-tone average method which uses low-frequency ranges underestimates the actual hearing los caused by the environmental lead and cadmium exposure”. Audiology and Neurotology 23 (2018): 259-269.
  7. Maria Angélica de Almeida Porto., et al. “Auditory evoked potentials in premature and full-term infants”. Brazilian Journal of Otorhinolaryngology5 (2011): 622-627.
  8. Khalili SAYA. “Hearing Loss”. Treasure Island (FL): StatPearls Publishing (2019).
  9. Cheng L-J SS., et al. “Cost-effectiveness analysis of bilateral cochlear implants for children with severe-toprofound sensorineural hearing loss in both ears in Singapore”. PLoS One (2019): 1-18.
  10. , et al. “The use of platelet-rich plasma in treatment of olfactory dysfunction: A pilot study”. Laryngoscope Investigative Otolaryngology 5.2 (2020): 1-7.
  11. BPS Tyagi., et al. “Platelet Rich Plasma (PRP): A Revolutionary Treatment of Sensorineural Hearing Loss”. Acta Scientific Otolaryngology4 (2019).
  12. Dohan Ehrenfest DM., et al. “Classification of platelet concentrates (Platelet-Rich Plasma-PRP, Platelet-Rich Fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives”. Muscles Ligaments Tendons Journal1 (2014): 3-9.
  13. Yao-wen Wang., et al. “Evaluation of intratympanic dexamethasone for treatment of refractory sudden sensorineural hearing loss”. Biomed and Biotechnology3 (2012): 203-208.
  14. S SRCaVR. “Hearing assessment in high-risk neonates by brain stem evoked auditory response (BERA) at a teaching hospital in rural Telangana”. Pediatric Review: International Journal of Pediatric Research8 (2016): 597-607.
  15. Qian Y ZS., et al. “Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases”. Otology and Neurotology8 (2018): 1018-1024.
  16. Apel PJ., et al. “Effect of locally delivered IGF-1 on nerve regeneration during aging: an experimental study in rats”. Muscle Nerve3 (2010): 335-341.
  17. Zackenfels K., et al. “Evidence for an important role of IGF-I and IGF-II for the early development of chick sympathetic neurons”. Neuron4 (1995): 731-741.
  18. Lutz BS., et al. “Effects of insulin-like growth factor-1 in motor nerve regeneration after nerve transection and repair vs. nerve crushing injury in the rat”. Acta Neurochirurgica (Wien)10 (1999): 1101-1106.


Citation: Brajpal Singh Tyagi. “Treatment of Sensorineural Hearing Loss in Children: Platelet Rich Plasma”. Acta Scientific Otolaryngology 3.2 (2021): 07-11.


Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

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