Abstract

Purpose: The purpose of this study is to determine the relation between the positron emission tomography/computed tomography (PET/CT) findings and post-operative pathology findings, which is a guiding characteristic for staging in patients with larynx cancer.

Materials and Methods: In order to evaluate the PET/CT in terms of diagnostics, preoperative PET/CT was applied to the patients who received laryngectomy ± neck dissection in 2013 - 2015 period. The specimens were examined in pathological terms, and the relation between the preoperative PET/CT and pathology findings of the tumor was investigated. The statistical analysis of the data was made with the NCSS 2007 computer program.

Results: The mean age of the patients who were included in the study was determined as 62, and the gender discrimination was as follows; 47 males and 3 females. A statistically significant difference was determined in the PET/CT (Mass - SUVmax) levels of the different groups of T (TNM) staging (p < 0.05); in which, the PET/CT (Mass-SUVmax) levels of the T₄ subgroup were higher than those of T_1-2 subgroups at a significant level (p = 0.015). Considering the tumor differentiation in histopathology, no statistically significant differences were detected between the PET-CT (Mass -SUVmax) levels of the tumors with various differentiations (p > 0.05).

Conclusion: The imaging methods used in larynx staging and in determining the treatment plan are inadequate. The use of PET/CT may change the proper surgical planning in terms of the staging of the disease.

Keywords: Laryngectomy; Laryngeal Neoplasms; Lymphatic Metastasis; Neck Dissection; Neoplasm Staging; PET-CT

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Citation

Citation: Doğan Çakan and Muhammet Gazi Yildiz. “Determining the Relation between PET/CT and Staging in Larynx Carcinoma". Acta Scientific Otolaryngology 3.1 (2020): 32-38.

Copyright

Copyright: © 2020 Doğan Çakan and Muhammet Gazi Yildiz. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.