Anshul Singh1 and Manish Gupta2*
1Senior Resident, Department of ENT, Maharishi Markandeshwar Institute of Medical Sciences and Research, MMDU, Ambala, India
2Professor and HOD, Department of ENT, Maharishi Markandeshwar Institute of Medical Sciences and Research, MMDU, Ambala, India
*Corresponding Author: Manish Gupta, Professor and HOD, Department of ENT, Maharishi Markandeshwar Institute of Medical Sciences and Research, MMDU, Ambala, India.
Received: August 24, 2020; Published: October 16, 2020
Oral squamous cell cancers usually metastasize by lymphatic route, to the neck lymph nodes and in few cases by hematogenous route to other organs. The perineural invasion is a less prevalent phenomenon. It occurs when the growth penetrates nerve sheath of nerve present in vicinity and grows alongside nerve bundle. It is associated with poor prognosis and high mortality as it is often missed preoperatively resulting in incomplete removal of the disease. Here we present a case of buccal carcinoma where the perineural spread along mandibular nerve led to malignancy spread to the skull base, causing inflammation of cavernous sinus and leading to lateral rectus palsy due to abducens nerve involvement.
Keywords: Oral Squamous Cell Carcinoma; Perineural Invasion; Base of the Skull Metastasis; Prognosis; Lateral Rectus Palsy; Cranial Nerve Infiltration
Citation: Anshul Singh and Manish Gupta. “Lateral Rectus Palsy: A Rare Sequel of Perineural Invasion by Oral Squamous Cell Carcinoma". Acta Scientific Otolaryngology 2.11 (2020): 09-12.
Copyright: © 2020 Anshul Singh and Manish Gupta. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.