Acta Scientific Otolaryngology (ASOL) (ISSN: 2582-5550)

Research Article Volume 2 Issue 8

Association of Laryngopharyngeal Symptoms and Signs with Gerd and its Response to Antireflux Therapy

Pramod Chirakkal* and Arunachalam Ravikumar

Department of ENT, Head and Neck Surgery, Sri Ramachandra University, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India

*Corresponding Author: Pramod Chirakkal, Department of ENT, Head and Neck Surgery, Sri Ramachandra University, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.

Received: June 17, 2020; Published: August 25, 2020

×

Abstract

Objectives: To determine the incidence of laryngopharyngeal symptoms and signs in GERD and assess the response to antireflux therapy.

Study Group: 30 patients will be selected for this study based on the inclusion and exclusion criteria formulated and will be evaluated with complete medical, clinical examination, videolaryngoscopic evaluation, Upper Gastro Intestinal endoscopy with biopsy and 24- hour pH monitoring (pre and post antireflux therapy).

Control Group: 10 adult healthy volunteers, from both sexes without any risk factor and without any laryngopharyngeal symptoms and symptoms suggestive of any dyspeptic disorders will be selected as controls.

Materials and Methods: The study group will be subjected to 6 weeks of anti-reflux precautions and antireflux therapy. Those whose laryngeal symptoms had improved or resolved will be again subjected to videolaryngoscopy, Upper Gastro Intestinal endoscopy with biopsy and 24 hr pH monitoring after 6 weeks of therapy. The same patients will be followed up for 6 months.

Results: The most frequent laryngopharyngeal symptoms with GERD were found to be difficulty in swallowing (83%), feeling of lump in the throat (73%) and burning sensation of throat (60%).

Conclusion: Gastro esophageal reflux disease (GERD) is a common disease, which impairs quality of life. Laryngopharyngeal symptoms are reliable predictors of GERD. The data-statistical analysis (Pearson Chi-Square test) used to support the findings of this study are included within the article.

Keywords: GERD; Antireflux; UGIE; H. Pylori

×

References

  1. Koufman JA. “The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury”. Laryngoscope 101 (1991): 1-78.
  2. Koufman Robert., et al. “Laryngopharyngeal reflux: Consensus conference report”. James Journal of Voice3 (1996): 215-319.
  3. Postma GN. “Ambulatory pH monitoring methodology”. The Annals of Otology, Rhinology and Laryngology 109 (2000): 10-14.
  4. James A Koufman., et al. “Laryngopharyngeal reflux: Position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-Head and Neck Surgery”. Otolaryngology - Head and Neck Surgery1 (2002): 32-35.
  5. Milstein CF., et al. “Prevalence of laryngeal irritation signs associated with reflux in asymptomatic volunteers: impact of endoscopic technique (rigid vs. flexible laryngoscope)”. Laryngoscope 12 (2005): 2256-2261.
  6. Nebel OT., et al. “Symptomatic gastroesophageal reflux: Incidence and precipitating factors”. The American Journal of Digestive Diseases21 (1976): 953.
  7. Dimenas E.“Methodological aspects of evaluation of quality of life in upper gastrointestinal diseases”. Scandinavian Journal of Gastroenterology 28 (1993): 18.
  8. Ziad Younes., et al. “Diagnostic evaluation in Gastroesophageal Reflux Disease”. Gastroenterology Clinics of North America 4 (1999): 809-831.
  9. Nigel Beasley. Anatomy of the larynx. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery, 7th ed.Great Britain, Hodder Arnold (2008): 2132.
  10. Nigel Beasley.“Anatomy of the pharynx and oesophagus. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery, ed 7.Great Britain, Hodder Arnold (2008): 1944.
  11. Nigel Beasley. Anatomy of the pharynx and oesophagus. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery, ed 7.Great Britain, Hodder Arnold (2008): 1944-1947.
  12. Nigel Beasley. Anatomy of the pharynx and oesophagus. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery, ed 7.Great Britain, Hodder Arnold (2008): 1951-1952.
  13. Mu L., et al. “Adult human upper esophageal sphincter contains specialized muscle fibers expressing unusual myosin heavy chain isoforms”. Journal of Histochemistry and Cytochemistry 3 (2007): 199-207.
  14. Lang IM., et al. “Videoradiographic, manometric and electromyographic assessment of upper esophagealsphincter”. American Journal of Physiology 260 (1991): G911-G919.
  15. Chirakkal P and Ravikumar A. “Laryngopharyngeal symptoms and signs in gastro esophageal reflux disease (GERD) and its response to antireflux therapy”.Clinical otolaryngology abstracts of the 14thBritish academic conference in otolaryngology posters-Laryngology37 (2012): 118-119.
×

Citation

Citation: Pramod Chirakkal and Arunachalam Ravikumar. “Association of Laryngopharyngeal Symptoms and Signs with Gerd and its Response to Antireflux Therapy". Acta Scientific Otolaryngology 2.9 (2020): 24-29.




Metrics

Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

Indexed In








News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 25, 2022.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US