Acta Scientific Otolaryngology (ASOL)

Review Article Volume 2 Issue 7

Salivary Testing as a Potential and Convenient Tool for Diagnosis of COVID 19

Amrapali Keny-Pawar*

Consultant Ear Nose Throat Surgeon, Asian Heart Institute and Research Centre, Mumbai, India

*Corresponding Author: Amrapali Keny-Pawar, Consultant Ear Nose Throat Surgeon, Asian Heart Institute and Research Centre, Mumbai, India.

Received: June 16, 2020; Published: June 26, 2020

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Abstract

RT-PCR (Reverse Transcription Polymerase chain Reaction) is the most commonly used laboratory test for detection of COVID 19 antigen. The test is done on samples obtained by using the Nasopharyngeal swab, Oropharyngeal swab, Sputum, bronchial secretions obtained via bronchial lavage or Saliva. The nasopharyngeal or oropharyngeal are currently commonly used for the same but several studies have shown that from the point of view of diagnosis, nasopharyngeal and throat swabs are less sensitive and specific as these material obtained from these areas reportedly contain less Viral RNA than sputum or saliva. Hence a more convenient and specific sample to test would be the saliva. The advantages of testing saliva (for RT-PCR) over other samples are discussed in this article.

Keywords: COVID 19; Salivary Testing; Corona Virus; Salivary Gland; Expression of ACE 2

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References

  1. D Sapkota., et al. “Saliva testing for COVID-19?” British Dental Journal 228 (2020): 658-659.
  2. Kelvin Kai-Wand To., et al. “Consistent Detection of 2019 Novel Coronavirus in Saliva”. Clinical Infectious Diseases (2020): ciaa149.
  3. Yi-Wei Tang., et al. “Laboratory Diagnosis Of COVID 19: Current Issues And Challenges”. Journal of Clinical Microbiology (2020).
  4. Lorenzo Azzi., et al. “Saliva Is A Reliable Tool To Detect SARS-CoV-2”. Journal of Infection (2020).
  5. Wengling Wang., et al. “Detection of SARS CoV-2 in different types of clinical specimen”. The Journal of the American Medical Association 18 (2020): 1843-1844.
  6. SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients”. The New England Journal of Medicine 382 (2020): 1177-1179.
  7. Divya Vinayachandran and Saravanakarthikeyan Balasubramanian “Salivary Diagnostics in COVID-!9: Future Research Implications”. Journal Of Dental Sciences (2020).
  8. Li Liu., et al. “Epithelial Cells Lining Salivary Gland Ducts Are Early Target Cells of Severe Acute Respiratory Syndrome Coronavirus Infection in the Upper Respiratory Tracts of Rhesus Macaques”. Journal of Virology 8 (2011): 4025-4030.
  9. Elisabeth Braun and Daniel Sauter. “Furin Mediated protein processing in infectious diseases and cancer”. Clinical and Translational Immunology 8 (2019): e1073.
  10. Ruoshi Xu., et al. “Saliva: potential diagnostic value and transmission of 2019-nCov”. International Journal of Oral Science 11 (2020).
  11. Marlus pedrosa., et al. “Salivary glands, saliva and oral presentations in COVID-19 infection”. Scientific Electronic Library (2020).
  12. J Xu., et al. “Salivary glands: potential Reservoirs for COVID-19 Asymptomatic Infection”. Journal of Dental Research (2020).
  13. E Pasomsub., et al. “Saliva sample as a non-invasive specimen for the diagnosis of coronavirus disease 2019: a cross – sectional study”. Clinical Microbiology and Infection (2020).
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Citation

Citation: Amrapali Keny-Pawar. “Salivary Testing as a Potential and Convenient Tool for Diagnosis of COVID 19". Acta Scientific Otolaryngology 2.7 (2020): 25-28.




Metrics

Acceptance rate34%
Acceptance to publication20-30 days
Impact Factor0.871

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