Soumya Bhowmik¹* and Kuljeet Singh Anand²

¹Consultant Neurologist, Department of Neurology, Institute of Neurosciences, Kolkata, India
²Prof and Ex HOD Department of Neurology, ABVIMS and Dr. RML Hospital, New Delhi India

*Corresponding Author: Soumya Bhowmik, Consultant Neurologist, Department of Neurology, Institute of Neurosciences, Kolkata, India.

Received: June 28, 2023; Published: August 18, 2023

Abstract

Clinical manifestation of acute corpus callosum (CC) infarction is complex and lacks specificity. Until there is a high index of suspicion it can be easily missed specifically in the early stage. We report a case of abrupt onset behavioural abnormality following recovery of COVID 19 infection, in a 30 year old female without any prior comorbidities. Her magnetic resonance imaging (MRI) brain revealed small midline DWI restriction at the splenium of the corpus callosam suggesting acute infarct. The typical symptoms of callosal infarction are consciousness or cognitive change, apraxia, such as alien hand syndrome with mild paralysis although in our case it is just an isolated abrupt onset behavioural change. Stroke following COVID 19 is not uncommon but acute onset mental status change following recovery from COVID 19 in a young lady without any apparent vascular risk factors showing MRI evidence of strategically located infarction in the splenium of corpus callosum without any other typical signs of callosal infarct is probably the first reported case in the literature.

Keywords: Corpus Callosal infarct, stroke, splenium of corpus callosum, COVID-19, Post COVID stroke

References

1. Zhang Z., et al. “Clinical Features, Etiology, and 6-Month Prognosis of Isolated Corpus Callosum Infarction”. BioMed Research International (2019): 9458039.
2. Kasow DL., et al. “Corpus callosum infarcts with atypical clinical and radiologic presentations”. American Journal of Neuroradiology 10 (2000): 1876-1880.
3. Sun X., et al. “Clinical, neuroimaging and prognostic study of 127 cases with infarction of the corpus callosum”. European Journal of Neurology 8 (2019): 1075-1081.
4. Nannoni S., et al. “Stroke in COVID-19: A systematic review and meta-analysis”. International Journal of Stroke 2 (2021): 137-149.
5. Oxley TJ., et al. “Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young”. The New England Journal of Medicine 20 (2020): e60.
6. Luo W., et al. “Ischemic stroke associated with COVID-19: a systematic review and meta-analysis”. Journal of Neurology 4 (2022): 1731-1740.
7. Yang LL., et al. “Clinical features of acute corpus callosum infarction patients”. International Journal of Clinical and Experimental Pathology 8 (2014): 5160-5164.

Citation

Citation: Soumya Bhowmik and Kuljeet Singh Anand. “An Interesting Case of Abrupt Onset Behavioural Abnormality in A Young Female Following Recovery from COVID-19". Acta Scientific Neurology 6.9 (2023): 21-23.

Copyright

Copyright: © 2023 Soumya Bhowmik and Kuljeet Singh Anand. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.