Acta Scientific Neurology (ISSN: 2582-1121)

Editorial Volume 4 Issue 1

Cerebral-neurological Manifestations of the Acute Respiratory Distress Syndrome (ARDS)

Ahmed N Ghanem*

Retired Consultant Urologist Surgeon and Independent Investigator, Mansoura University, Faculty of Medicine, Egypt

*Corresponding Author: Ahmed N Ghanem, Retired Consultant Urologist Surgeon and Independent Investigator, Mansoura University, Faculty of Medicine, Egypt.

Received: December 20, 2020; Published: December 30, 2020


Substantial evidence currently exists demonstrating that volumetric overload (VO) complicates fluid therapy (FT) of shock inducing VO shocks (VOS) [1] that cause the acute respiratory distress syndrome (ARDS) [2,3]. These most serious morbidities and mortalities affect hundreds of thousand cases every year all over the world but remained overlooked, unrecognized, and underestimated. Cerebral and neurological manifestations of both VOS and ARDS are the commonest and most prevalent among the clinical features of the multiple organ dysfunction syndrome (MODS) that represent ARDS (Table 1), presenting mainly with deep coma of the highest grade.



  1. Ghanem AN. “Volume Kinetic (VK) Shock or Volumetric Overload Shocks (VOS) In Surgical Patients”. Journal of Biomedical Science and Research 3 (2020): 128.
  2. Ghanem AN. “Volumetric overload shocks cause the acute respiratory distress syndrome: The plenary evidence on patho-aetiology and therapy”. Journal of Bio-Science 4 (2020): 1-9.
  3. Ghanem AN. “Volumetric Overload Shocks Cause the Acute Respiratory Distress Syndrome: Building the Bridge Between Physics, Physiology, Biochemistry, and Medicine”. Biomedical Journal of Scientific and Technical Research 1 (2020).
  4. Ghanem AN. “Update on Ghanem’s new scientific discoveries in physics”. Physiology, and Medicine, Research in Infectious Diseases and Tropical Medicine1 (2020): 52-57.
  5. Ghanem AN and Ward JP. “Osmotic and metabolic sequelae of volumetric overload in relation to the TURP syndrome”. British Journal of Urology 66 (1990): 71-78.
  6. Ghanem AN. “The Adult Respiratory Distress Syndrome: Volumetric Overload Shocks in Patho-Etiology, Correcting Errors and Misconceptions on Fluid Therapy, Vascular and Capillary Physiology”. Surgical Medicine Open Access Journal 2 (2018).
  7. Ghanem AN. “What are Misleading Physicians into giving too much Fluid During Resuscitation of Shock and Surgery that Induces ARDS and/or AKI?”. Asploro Journal of Biomedical and Clinical Case Reports1 (2020): 90-98.
  8. Ghanem AN. “Magnetic field-like fluid circulation of a porous orifice tube and relevance to the capillary-interstitial fluid circulation: Preliminary report”. Medical Hypotheses3 (2001): 325-334.
  9. Ghanem KA and Ghanem AN. “The proof and reasons that Starling’s law for the capillary-interstitial fluid transfer is wrong, advancing the hydrodynamics of a porous orifice (G) tube as the real mechanism”. Blood, Heart and Circulation 1 (2017): 1-7.
  10. Hahn RG. “Adverse effects of crystalloid and colloid fluids”. Intensive Therapy 49.4 (2017): 303-308.
  11. Hahn RG. “REVIEW ARTICLE Understanding volume kinetics”. Acta Anaesthesiologica Scandinavica (2020): 1-9.
  12. Rowan KM., et al. “PRISM Investigators, Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis”. The New England Journal of Medicine 23 (2017): 2223-2234.
  13. Huang DT., et al. “ProCESS/ARISE/ProMISe Methodology Writing Committee, harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe”. Intensive Care Medicine10 (2013): 1760-1775.
  14. Jones DG., et al. “Crystalloid resuscitation in trauma patients: deleterious effect of 5L or more in the first 24h”. BMC Surgery1 (2018): 93.
  15. Coons BE., et al. “High volume crystalloid resuscitation adversely affects paediatric trauma patients”. Journal of Pediatric Surgery 11 (2018): 2202-2208.
  16. Schrier RW. “Fluid administration in critically ill patients with acute kidney injury”. Clinical Journal of the American Society of Nephrology4 (2010): 733-739.


Citation: Ahmed N Ghanem. “Cerebral-neurological Manifestations of the Acute Respiratory Distress Syndrome (ARDS)". Acta Scientific Neurology 4.2 (2021): 01-03.


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