Shankar Prasad Bhattacharya
Associate Professor, Community Medicine, MJNMC, Coochbehar, West Bengal, India
*Corresponding Author: Shankar Prasad Bhattacharya, Associate Professor, Community Medicine, MJNMC, Coochbehar, West Bengal, India.
Received: October 09, 2025; Published: January 09, 2026
Fatty Liver Disease refers to the abnormal accumulation of fat in the liver cells. When this occurs without significant alcohol intake, it is termed Non-alcoholic Fatty Liver Disease (NAFLD) — recently reclassified as Metabolic dysfunction-associated steatotic liver disease (MASLD) in international consensus to emphasize its metabolic roots. NAFLD/MASLD ranges from simple steatosis to non- alcoholic steatohepatitis (NASH), which may progress to fibrosis, cirrhosis and hepatocellular carcinoma. The condition is closely linked to metabolic syndrome components including obesity, insulin resistance, and dyslipidaemia. Globally, NAFLD has become the most common chronic liver disease, influencing health outcomes and healthcare systems across high- and low-income countries alike due to lifestyle changes, sedentary behaviour and rising prevalence of diabetes and obesity. Early detection and lifestyle intervention are crucial, as progression can lead to irreversible liver damage and increased cardiometabolic risk.
Keywords: Fatty Liver Disease; Non-alcoholic Fatty Liver Disease (NAFLD); MASLD; Metabolic Dysfunction; Steatosis; Cirrhosis; Metabolic Syndrome; Obesity; Diabetes
Citation: Shankar Prasad Bhattacharya. “Overview of Fatty Liver Disease". Acta Scientific Medical Sciences 10.2 (2026): 05-06.
Copyright: © 2026 Shankar Prasad Bhattacharya. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.