Fernando Solarz, Janeth Lara Alcántara*, Iara Izquierdo M, M Florencia Arabena Bilbao, Facundo Salazar Molina, M Paula Pinto, Johanna Costa and Patricio Servienti

Oncology Service, General Acute Care Hospital, Dr. Teodoro Álvarez, Buenos Aires, Argentina

*Corresponding Author: Janeth Lara Alcántara Oncology Service, General Acute Care Hospital, Dr. Teodoro Álvarez, Buenos Aires, Argentina.

Received: August 18, 2025; Published: December 22, 2025

Abstract

Ovarian carcinosarcoma (OCS), also known as malignant mixed Mullerian tumor (MMMT), is a rare and aggressive tumor, accounting for less than 3% of ovarian cancers. It has a high morbidity and mortality rate, with an overall survival rate of less than two years.

There are factors that can increase the risk of OCS, as well as factors that contribute to a poor prognosis.

We present the case of a patient recently diagnosed with OCS and review the literature.

 Keywords: Ovarian Carcinosarcoma; Malignant Mixed Mullerian Tumor

References

1. McFarlane I., et al. “Ovarian carcinosarcoma is highly aggressive compared to other ovarian cancer histotypes”. Frontiers in Oncology 14 (2024): 1399979.
2. Kim HJ., et al. “Prognostic assessment of sarcomatous histologic subtypes of ovarian carcinosarcoma”. Obstetrical and Gynecological Science4 (2017): 350-356.
3. Mano MS., et al. “Current management of ovarian carcinosarcoma”. International Journal of Gynecological Cancer2 (2007): 316-324.
4. Ho GY., et al. “Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin”. Cancer Research23 (2002): 4457-4473.
5. Rauh-Hain JA., et al. “Carcinosarcoma of the ovary compared to papillary serous ovarian carcinoma: a SEER analysis”. Gynecologic Oncology1 (2013): 46-51.
6. Cantrell LA and Van Le L. “Carcinosarcoma of the ovary a review”. Obstetrical and Gynecological Survey10 (2009): 673-80; quiz 697.
7. Ha HI., et al. “Incidence and treatment outcomes of ovarian carcinosarcoma from the national cancer registry of Korea”. Journal of Gynecologic Oncology1 (2024): e31.

Citation

Citation: Janeth Lara Alcántara., et al. “Ovarian Carcinosarcoma: Case Report and Literature Review”.Acta Scientific Medical Sciences 10.1 (2026): 57-59.

Copyright

Copyright: © 2026 Janeth Lara Alcántara., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.