Chronic Calcific Pancreatitis with Multi-System Involvement and Alcohol Dependence Syndrome: Case Report

KNV Adithya* and Rahul Dhanabalan B

Department of General Medicine, Panimalar Medical College Hospital and Research Institute, Poonamallee, Chennai, India

*Corresponding Author: KNV Adithya, Assistant Professor, Department of General Medicine, Panimalar Medical College Hospital and Research Institute, Poonamallee, Chennai, India.

Received: March 31, 2025; Published: September 30, 2025

Abstract

Chronic calcific pancreatitis (CCP) is a progressive fibro-inflammatory disorder of the pancreas, commonly associated with long-term alcohol consumption. It can lead to multi- system complications, including hepatobiliary dysfunction, metabolic derangements, and cardiovascular events. We report a case of a 36-year-old male with CCP, complicated by ascending cholangitis, acute kidney injury (AKI), atrial fibrillation (AF), and alcohol dependence syndrome, highlighting the need for multidisciplinary management in such complex presentations.

 Keywords: Chronic Calcific Pancreatitis (CCP); Acute Kidney Injury (AKI)

References

1. Etemad B and Whitcomb DC. “Chronic pancreatitis: diagnosis, classification, and new genetic developments”. Gastroenterology3 (2001): 682-707.
2. Yadav D and Lowenfels AB. “The epidemiology of pancreatitis and pancreatic cancer”. Gastroenterology 6 (2013): 1252-1261.
3. Meier JJ and Nauck MA. “Chronic pancreatitis, diabetes, and pancreatogenic diabetes mellitus”. Gastroenterology 2 (2010): 456-465.
4. Bang UC., et al. “Mortality, cancer, and comorbidities in patients with chronic pancreatitis: a Danish nationwide matched-cohort study”. Gastroenterology4 (2014): 989-994.
5. Lankisch PG., et al. “Acute pancreatitis”. The Lancet9988 (2015): 85-96.
6. Kocer B., et al. “Acute pancreatitis and its relationship with atrial fibrillation”. American Journal of Emergency Medicine 2 (2016): 261-265.
7. Rehm J., et al. “Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders”. The Lancet9682 (2009): 2223-2233.
8. Braganza JM., et al. “Chronic pancreatitis”. The Lancet9772 (2011): 1184-1197.
9. Trikudanathan G., et al. “New developments in acute pancreatitis”. Gastroenterology 7 (2019): 1974-1985.

Citation

Citation: KNV Adithya and Rahul Dhanabalan B. “Chronic Calcific Pancreatitis with Multi-System Involvement and Alcohol Dependence Syndrome: Case Report”.Acta Scientific Medical Sciences 9.10 (2025): 87-89.

Copyright

Copyright: © 2025 KNV Adithya and Rahul Dhanabalan B. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.