Shahad Hassan Alzahrani¹*, Alyah Bandar Almutairi², Bashayer Ali Alanazi², Heba Ammar Almutairi², Sara Majed Alhawashi³, Ebtehal Saeed Albogami³, Shahad Saleh Alsalhi³, Raghad Ali Aloqayli⁴, Ghadi Abdullah AlQarni⁴ and Maha Salem Alshamsy⁵

¹Respiratory Therapy Specialist Respiratory Care Services, Pediatric Department, Prince Sultan Military City, Riyadh, Saudia Arabia
²Respiratory Therapy Technician, Respiratory Care Services, Pediatric Department, Prince Sultan Military City, Riyadh, Saudia Arabia
³Respiratory Therapy Specialist Adult Intensive Care Services, Respiratory Care Department, Prince Sultan Military City, Riyadh, Saudia Arabia
⁴Respiratory Therapy Technician, Adult Intensive Care Services, Respiratory Care Department, Prince Sultan Military City, Riyadh, Saudia Arabia
⁵Respiratory Therapy Specialist Respiratory Care Services, Gama Hospital, Khobar, Saudia Arabia

*Corresponding Author: Shahad Hassan Alzahrani, Respiratory Therapy Specialist Respiratory Care Services, Pediatric Department, Prince Sultan Military City, Riyadh, Saudia Arabia.

Received: March 24, 2025; Published: April 14, 2025

Abstract

Background: Acute Respiratory Distress Syndrome characterized by Refractory hypoxemia, inflammation, and alveolar destruction, which necessitates mechanical ventilation. In order to minimize ventilator-induced lung damage and lower mortality, ventilatory methods must be used. This systematic review aims to assess various ventilation methods utilized in intensive care units for critically sick patients to lower death rates and ventilation time.

Method: This study was conducted according to The PRISMA statement. We conducted a search of electronic databases (PubMed, Scopus, and Google scholar) for articles on mortality rate and duration of invasive mechanical ventilation in patients suffering from acute respiratory distress syndrome published in the period from 2016 to 2024. We include randomized controlled trials, prospective and retrospective cohort studies, and observational studies.

Result and Conclusion: We include 7 articles in this review, the included studies discussed different ventilation strategies and their effect on mortality rates and mechanical ventilation duration in critically ill patients. The findings from the included studies show the role of lung-protective ventilation, prone positioning, high-frequency oscillatory ventilation, extracorporeal membrane oxygenation, oxygenation targets, and spontaneous breathing trials in the improvement of patient outcomes. We found that lung-protective strategies, early mobilization, and adjunctive interventions were needed to reduce mortality and ventilation duration in critically ill patients. LTVV, prone positioning, HFOV, ECMO, and oxygenation target optimization emerged as an important strategies to improve outcomes.

 Keywords: Mortality Rate; Duration of Invasive Mechanical Ventilation; Acute Respiratory Distress Syndrome

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Citation

Citation: Shahad Hassan Alzahrani., et al. “Practices to Lower the Mortality Rate and Duration of Invasive Mechanical Ventilation in Patients Suffering from Acute Respiratory Distress Syndrome; Systematic Review”.Acta Scientific Medical Sciences 9.5 (2025): 74-80.

Copyright

Copyright: © 2025 Shahad Hassan Alzahrani., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.