Yanier Espinosa-Goire¹*, José Manuel Padilla González¹, Luis Manuel Abreu Pereira² and Andy Guillermo Paumier Durán¹

¹Guantanamo University of Medical Sciences, Guantanamo School of Medical Sciences, Guantanamo, Cuba
²Havana University of Medical Sciences, Mayabeque School of Medical Sciences, Mayabeque, Cuba

*Corresponding Author: Yanier Espinosa-Goire, Guantanamo University of Medical Sciences, Guantanamo School of Medical Sciences, Guantanamo, Cuba.

Received: September 23, 2024; Published: October 14, 2024

Abstract

Introduction: Antimicrobial resistance (AMR) is a natural evolutionary response to exposure to antimicrobials. By 2050, approximately 10 million deaths are expected annually, directly or indirectly displacing neoplasia as the leading cause of death. Staphylococcus aureus is a gram-positive pathogenic bacterium with an incidence of 20 to 50 cases per year.

Objective: To describe the behavior of microbial drug resistance in Staphylococcus aureus.

Material and Methods: A bibliographic review was carried out between July and August 2024, of 26 references in Spanish and English in the SciELO, Elsevier, PubMed and Google Scholar search engine databases. The most recent published literature in accordance with the novelty of the topic in question was considered as a selection criterion.

Development: Staphylococcus aureus has particular characteristics of virulence and resistance to antibiotics. It presents indigenous forms of resistance: it reduces membrane permeability, limits drug absorption and the flow system by promoting drug leakage and the overproduction of β-lactamase. Resistance to methicillin and β-lactam antibiotics is determined in more than 85% by the presence of the mecA gene.

Conclusions: Antimicrobial resistance is a threat to human, animal and environmental health. Staphylococcus aureus is a microorganism that has very distinctive characteristics regarding its virulence and pathogenicity factors of resistance to various antibiotics. Several studies agree that resistance to methicillin and β-lactam antibiotics is determined in more than 85% by the mecA gene.

 Keywords: Behavior; Drug Resistance Microbial; Staphylococcus aureus

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Citation

Citation: Yanier Espinosa-Goire., et al. “Drug Resistance Microbial of Staphylococcus aureus”.Acta Scientific Medical Sciences 8.11 (2024): 66-70.

Copyright

Copyright: © 2024 Yanier Espinosa-Goire., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.