Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 8 Issue 9

Leucocytes and Cd4 Counts of Individuals Exposed to Wood Dust in Ekpoma, Edo State, Nigeria

Babatope IO1*, Omonkhuale FM1 and Iyevhobu KO2

1Department of Haematology and Blood Transfusion Science, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Nigeria
2Department of Medical Microbiology, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Nigeria

*Corresponding Author: Babatope IO, Department of Haematology and Blood Transfusion Science, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Nigeria.

Received: June 20, 2024; Published: August 13, 2024

Abstract

Exposure to wood dust may result in external and internal health problems which may be immediate, short-term or long-term. This study was carried out to evaluate the leucocytes and CD4 counts of individuals exposed to wood dust in Ekpoma, Edo State, Nigeria. A total of fifty individuals exposed to wood dust aged 16-60 years and of both sexes were recruited for this study. Fifty apparently healthy subjects who were not exposed to wood dust served as control. The leucocyte counts were carried out using Sysmex KX-21N Autoanalyzer and the CD4 count was determined using Flow Cytometry. In this study, the results obtained showed that the CD4 count (cells/µL) of the test subjects and control subjects were 912.60 ± 298.05 and 891.14 ± 304.61 respectively. Similarly, total leucocyte counts (x10³/μl) of both test and control subjects were 5.44 ± 1.34 and 5.34 ± 1.74 respectively. Furthermore, LYM % of the test subjects and control subjects was 41.76 ± 10.87 and 49.48 ± 8.67, NEUT % was 45.58 ± 10.19 and 37.74 ± 8.39, while MXD % was 12.38 ± 4.96 and 11.65 ± 3.69 respectively. Neutrophil % was significantly higher while lymphocyte % was significantly lower. There was a statistically significant increase in CD4 count of female subjects compared to males. Age did not affect any of the parameters studied except total leucocyte count. Duration of exposure to wood dust did not affect any of the parameters studied. In conclusion, neutrophil %, lymphocyte % and CD4 count were variably affected by wood dust. Similarly, the WBC total count of subjects in the age bracket of 51 years and above was significantly higher compared to other age groups. However, duration of exposure to wood dust did not affect any of the parameters studied. We hereby recommend that individuals exposed to wood dust should be encouraged to use Personal Protective Equipment (PPE) such as face mask while working to reduce exposure.

 Keywords: Leucocytes; CD4; Wood; Dust; Haematology

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Citation

Citation: Babatope IO., et al. “Leucocytes and Cd4 Counts of Individuals Exposed to Wood Dust in Ekpoma, Edo State, Nigeria”.Acta Scientific Medical Sciences 8.9 (2024): 63-69.

Copyright

Copyright: © 2024 Babatope IO., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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