ShA Topchiyeva¹*, LZ Yildiz², N Gorgaslidze³, TM İsgenderov¹ and SM Mammadova¹

¹Institute of Zoology of the Ministry of Science and Education of the Republic of Azerbaijan
²Tokat Gaziosmasha University, Department of Basic Medical Sciences/Physiology, Turkey
³Tbilisi State Medical University, Head of The Department of Sosial and Clinical Pharmacy, Tbilisi, Georgia

*Corresponding Author: ShA Topchiyeva, Institute of Zoology of the Ministry of Science and Education of the Republic of Azerbaijan.

Received: March 18, 2024; Published: June 05, 2024

Abstract

The article presents data from experimental studies to identify the biochemical and physicochemical characteristics of the venom of the viper (Macrovipera lebetina obtusa Linnaeus, 1758) with different shelf life. The purpose of the presented work is to study the biochemical and physicochemical parameters of viper venom (Macrovipera lebetina obtusa Linnaeus, 1758) with different shelf life. To achieve this goal, we conducted experimental studies with samples of viper venom collected over the period of time 1989, 1991, 1993, 2010 and 2015. The activity of enzymes in samples of venom from the Transcaucasian viper was determined by the titrometric method. The resistance was measured with an E6-13A teraohmmeter. The photosensitivity of snake venom was studied based on photoconductivity measurements in the wavelength region of 0.2-2 μm. It has been established that viper venom crystals are not photosensitive in the wavelength range of 0.2-2 μm, but viper venom has photoconductivity in the wavelength range 2-4 μm. It has been experimentally established that in samples of viper venom collected in 2015, the content of proteolytic activity is 2.73, 2.0, 1.46, 1.71 times higher than in venom samples collected in 1989, 1991, 1993, 2010, respectively. The level of L-amino acid oxidase activity in venom samples collected in 2015 was detected, the level of which corresponded to 0.30 IU/mg. In samples of viper venom collected in 2015, the content of L-amino acid oxidase is 3.33, 2.73, 2.0, 1.15 times higher than in samples collected in 1989, 1991, 1993, 2010, respectively.

 Keywords: Comparative Data; Biochemical; Physicochemical; Venom; Viper

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Citation

Citation: ShA Topchiyeva., et al. “Comparative Data on the Biochemical and Physicochemical Characteristics of the Venom of Viper (Macrovipera Lebetina Obtusa Linnaeus, 1758) with different Shelf Life”.Acta Scientific Medical Sciences 8.7 (2024): 34-38.

Copyright

Copyright: © 2024 ShA Topchiyeva., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.