Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 8 Issue 6

Pathophysiological Mechanisms of the Therapeutic Effectiveness of Oxidized Dextrane in Violations of Spermatogenesis of Infectious and Inflammatory Genesis

EG Novikova1,2, AV Troitsky1*, TN Bystrova1, EH Churina3,4 and OI Urazova3

1Federal Research Centre for Fundamental and Translational Medicine, Novosibirsk, Russia
2Regional Medical and Diagnostic Center, Novosibirsk, Russia
3Federal State Budget Educational Institution of Higher Education "Siberian State Medical University" of the Ministry of Health of the Russian Federation, Russian Federations, Tomsk, Moscow Tract, Russia
4Federal State Autonomous Educational Institution of Higher Education "National Research Tomsk State University" 4; 634050, Tomsk, Russia

*Corresponding Author: AV Troitsky, Federal Research Centre for Fundamental and Translational Medicine, Novosibirsk, Russia.

Received: April 23, 2024; Published: May 27, 2024

Abstract

Currently, among the etiological factors of impaired spermatogenesis, infectious and inflammatory processes are considered to be the most common. And this applies not only to urogenital infections, but also to any chronic infectious processes caused by both bacteria and pathogenic fungi and viruses.

 Keywords: Immunity; Fertility; Herpes

References

  1. Kovalyk VP., et al. “The role of herpesviruses in male infertility’. M.G. Medical examination 5.3 (2021): 123-129.
  2. Demiashkin GA., et al. “Effects of SARS-CoV-2 infection on male and female reproductive systems (meta-analysis)”. Medical Journal of the Caucasus4 (2020): 582-586.
  3. Adamyan LV., et al. “The influence of COVID-19 and other viral infections on male fertility (review of literature)”. Reproductive Problems6 (2020): 77-82.
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  9. Novikova EG., et al. “The use of rectal suppositories with oxidized dextrane in calculated prostatitis”. Urology 6 (2021): 1270129.
  10. Troitsky AV., et al. “Prospects of the use of oxidized dextran for the prevention of viral pneumonia and pulmonary fibrosis”. Medical Alliance4 (2014): 45-53.
  11. WHO Laboratory Guide to the Research and Treatment of Human Sperm. 5th ed., 2010. Per. with Angl. N. P. Makarov. Scientist. ex. L. F. Kurilo. Moscow: Capital Print, 2012. (WHO Guide to Human Ejaculate Research and Treatment, ed. 5, 2010. Per. with Angl. N.P. Makarov. Scientific editor L. F. Kurilo. M.: Capital Print, (2012).
  12. Figueiredo AFA., et al. “Activation of C-C motif chemokine receptor 2 modulates testicular macrophages number, steroidogenesis, and spermatogenesis progression”. Cell Tissue Research1 (2021): 173-190.
  13. Lukyanenko YO., et al. “Production of 25-hydroxycholesterol by testicular macrophages and its effects on Leydig cells”. Biology Reproduction3 (2001): 790-796.
  14. Novikova EG., et al. “Experimental study of the effectiveness of rectal suppositories with oxidized dextran in prostate hyperplasia”. Urology 5 (2021): 59-61.

Citation

Citation: AV Troitsky., et al. “Pathophysiological Mechanisms of the Therapeutic Effectiveness of Oxidized Dextrane in Violations of Spermatogenesis of Infectious and Inflammatory Genesis”.Acta Scientific Medical Sciences 8.6 (2024): 111-118.

Copyright

Copyright: © 2024 AV Troitsky., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Impact Factor1.403

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