Dr. Anusha Sunder¹* and Gomathy Shivaji²

¹Doctorate in Lifescience/Human Nutrition, Accredited Certification in Nutrigenetics, Lead Scientist and Nutrigenetic Expert, Xcode Life Sciences, Pvt. Ltd. Chennai, India
²Head of the Department (Retd.), Department of Human Science, Women’s Christian College, Chennai, India

*Corresponding Author: Dr. Anusha Sunder, Doctorate in Lifescience/Human Nutrition, Accredited Certification in Nutrigenetics, Lead Scientist and Nutrigenetic Expert, Xcode Life Sciences, Pvt. Ltd. Chennai, India.

Received: May 06, 2024; Published: May 22, 2024

Abstract

Circulating levels of omega-3 PUFA and their erythrocyte membrane levels (omega-3 index) inversely associate with cardiovascular events. As flaxseed oil and fish oil have complementary cardioprotective benefits, the combined effect of a daily supplementation of ALA (868.98 mg), EPA (358.2 mg) and DHA (238.4 mg) was studied in pre-obese, mild hypercholesterolemic women using a pre-test, post-test research design. 30 premenopausal and 30 postmenopausal subjects (equally assigned to control and test groups) underwent two week baseline, 60 days study/supplementation and two week withdrawal (test group alone) periods. The combined supplementation was significantly hypocholesterolemic, hypotensive, anti-inflammatory and obesity-lowering alongside improving omega-3 index.

 Keywords: PUFA (Polyunsaturated Fatty Acids); ALA (Alpha-linolenic Acid); EPA (Eicosapentaenoic Acid); DHA (Docosahexaenoic Acid); Mild Hypercholesterolemia (Total Cholesterol-200 to 239 mg/dL); Omega-3 Index (Sum of EPA and DHA in the Erythrocyte Membrane, Expressed in Percentage); LDL-C (Low Density Lipoprotein Cholesterol); VLDL-C (Very Low Density Lipoprotein Cholesterol); HDL-C (High Density Lipoprotein Cholesterol)

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Citation

Citation: Dr. Anusha Sunder and Gomathy Shivaji. “An Up-to-date Marker of Heart Health - The Omega-3 Index!”.Acta Scientific Medical Sciences 8.6 (2024): 79-84.

Copyright

Copyright: © 2024 Dr. Anusha Sunder and Gomathy Shivaji. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.