Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 8 Issue 1

Clinical Profile of Infections in the First Year Post Renal Transplantation - A Prospective Cohort Study from a Tertiary Care Hospital in South-western India

Angela Philips1 and Betha Prudvi Tarun2*

1Internal Medicine Resident, Jehangir Hospital, Pune, India
2Internal Medicine Resident, Poona Hospital and Research Center, Pune, India

*Corresponding Author: Betha Prudvi Tarun, Internal Medicine Resident, Poona Hospital and Research Center, Pune, India.

Received: December 04, 2023; Published: December 14, 2023

Abstract

Introduction: Management of infectious complications is a big problem in kidney recipients. The infection rate is dependent on the environment, social, and financial factors. India has the second largest kidney transplantation programme after United states of America. Yet, there is a paucity of data on kidney transplantations in Indian population. This study hopes to address this gap.

Aims and Objectives

  • To study the incidence of infections in renal transplant recipients.
  • To evaluate the clinical profile of presentation in these patients.
  • To find the aetiology of the infections.
  • To assess the outcome of these patients.

Methods: Around 46 patients were assessed in Jehangir hospital post renal transplant for a period of one year and incidence of infection within 1 month, 1 to 6 months and greater than 6 months was assessed with type of infection like bacterial, viral, and fungal. In bacterial infection types of organism was identified. Risk factors like DJ stent, female gender, type of induction, ABO incompatibility was assessed.

Results: In renal transplant recipient, the rate of infection is maximum in the 2-6 months after transplantation and is UTI due to Escherichia coli was found to be most common cause followed by Klebsiella pneumoniae. More infection episodes occurred in Males. It was found that infections occurred more frequently in the age group 50-59 years and in individuals with comorbidities. DJ stenting was associated with increased frequency of infections during 1st month after transplantation. There was no statistical association found for infection episodes and female gender, type of induction used, type of donor whether living or cadaveric, DJ stenting.

 Keywords: Klebsiella pneumoniae; Kidney Transplantation; Escherichia coli

 

References

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Citation

Citation: Angela Philips and Betha Prudvi Tarun. “Clinical Profile of Infections in the First Year Post Renal Transplantation - A Prospective Cohort Study from a Tertiary Care Hospital in South-western India”.Acta Scientific Medical Sciences 8.1 (2024): 26-32.

Copyright

Copyright: © 2024 Angela Philips and Betha Prudvi Tarun. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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