Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 7 Issue 8

Assessment of Lipid Profile on Patients with Pulmonary Tuberculosis

Airhomwanbor KO1, Iyevhobu KO2*, Omolumen LE1, Idehen CI3, Akhere PI4, Asibor E3, Akomolafe BK5, Ikyaagba RO6 and Imagbosoria S1

1Department of Chemical Pathology, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria
2Department of Public Health, National Open University of Nigeria, Uromi Community Study Centre, Uromi, Edo State, Nigeria
3Department of Histopathology, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria
4Department of Obstretrics and Gynaecology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria
5Faculty of Basic Medical and Applied Sciences, Lead City University, Ibadan, and Oyo State Primary Health care Board, Nigeria
6Raigmore Hospital, Inverness, Scotland, United Kingdom

*Corresponding Author: Iyevhobu KO, Department of Public Health, National Open University of Nigeria, Uromi Community Study Centre, Uromi, Edo State, Nigeria.

Received: June 19, 2023; Published: July 25, 2023


Tuberculosis is one of the first most common causes of deaths in the world alongside HIV/AIDS, causing more than 9.6 million new cases and 1.5 million deaths globally in 2014 alone. This infection also accompanied by lipid profile alterations. The lipid alteration related to the disease is not yet well determined and has variation in different studies. The present study was conducted with the objective to find out lipid profile in newly diagnosed tuberculosis patients. This study aimed at evaluating the lipid profiles in pulmonary tuberculosis patients. A total of eighty (80) subjects were recruited for this study which consists of forty (40) patients with pulmonary tuberculosis out of which twenty (20) were new cases, ten (10) two months patients with pulmonary tuberculosis therapy and ten (10) six months patients with pulmonary tuberculosis therapy and forty (40) apparently healthy individuals which served as control. Collected bloods were tested using Mindray chemistry analyzer lipid profiles. The mean serum levels of triglyceride, total cholesterol, high density lipoprotein and low-density lipoprotein were significantly lower than their respective control groups (p = 0.001). Pulmonary Tuberculosis patients in this study had lipid profile abnormalities. Total Cholesterol, HDL, LDL and TG concentrations were significantly reduced as compared with control groups. The factors associated with Lipid profiles also due attention to prevent further complication. This study concludes that parameters of lipid profile were deranged in our tuberculous cases. To achieve maximum response of TB treatment we must consider normalizing lipid profile along with standard treatment for better recovery.

 Keywords: Pulmonary; Tuberculosis; Mycobacterium tuberculosis; Total Cholesterol; HDL; LDL and TG


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Citation: Airhomwanbor KO., et al. “Assessment of Lipid Profile on Patients with Pulmonary Tuberculosis”.Acta Scientific Medical Sciences 7.8 (2023): 198-207.


Copyright: © 2023 Airhomwanbor KO., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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