Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 7 Issue 8

Obstacles to Blood Donation and the Prevalence of Sickle Cell Trait at the Bafoussam Regional Hospital Blood Bank, West - Cameroon

Thomas Djifack Tadongfack1*, Delia Vadette Mafoza1, Ariane Lagranche Beasso Tadongfack2, Monique Odette Kamtchueng3, Irina Lydia Sudeu Nitcheu4, Boris Dior Andela Satoun5, Cyrille Wanvoum6, Freddy Ndadjeu Njombi6, Carine Tsoplifak Kenfack7, Normand David Ebonda4 and Michael Junior Piameu Chadou4

1Medical Laboratory Department, Saint Vincent de Paul Hospital Dschang, Cameroon
2Department of Biochemistry, Faculty of Science, University of Douala, Cameroon
3Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang, Cameroon
4School of Health Sciences, Catholic University of Central Africa Yaoundé, Cameroon
5Centre for Drug Research Enhance against AIDS and Malnutrition (DREAM) Dachang, Cameroon
6Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Cameroon
7School of State registered Nurses of Bafoussam, Cameroon

*Corresponding Author: Thomas Djifack Tadongfack, Medical Laboratory Department, Saint Vincent de Paul Hospital Dschang, Cameroon.

Received: June 21, 2023; Published: July 04, 2023


Healthy blood transfusion contributes to saving millions of lives each year, while improving the life expectancy and quality of life of patients with life-threatening diseases and other conditions. The present study aimed to determine the characteristics, attitude of blood donors and the prevalence of sickle cell trait at the Bafoussam Regional Hospital Blood Bank (BRHBB). This was a quantitative descriptive cross-sectional study, conducted over a period of one month and including a total of 185 blood donors received at BSHRB. A structured questionnaire was used to assess the participants' characteristics and attitudes towards blood donation. After measurement of blood pressure, pulse, weight, height and haemoglobin level, a sample of approximately 4 mL of blood was collected and used for blood grouping and haemoglobin electrophoresis assay for sickle cell trait determination. Statistical analysis was performed using SPSS version 25 software. Participants aged between 21 and 39 years were the most represented age group with a frequency of 48.1%. 85.9% of the study population were male. Potential donors reported for high systolic or diastolic blood pressure represented 35.8% of the study population. More than half (55.7%) were overweight or obese. Only 8.1% of blood donations were voluntary. 70.8% of donors had 1 to 3 sexual partners. Rhesus D positive O and A phenotypes were the most frequent with proportions of 53.0% and 23.8% respectively. Sickle cell trait was found in 14.6% of the donor population. There is a need to intensify the education of the population on voluntary blood donation, the retention of replacement family donors and the systematic screening of sickle cell trait before blood donation in all hospital blood banks and blood transfusion centres. This will ensure the availability of more healthy blood products and a safer transfusion in Cameroon.

 Keywords: Obstacles; Blood Donation; Sickle Cell Trait


  1. “Blood transfusion safety” (2021).
  2. “Sécurité transfusionnelle et approvisionnement en sang” (2021).
  3. NBTP - National Blood Transfusion Programme. “Let’s give blood to save lives” (2021).
  4. ONU Info. “L’OMS souligne le besoin de davantage de donneurs de sang volontaires” 2013 (2021).
  5. Tagny CT., et al. “Blood safety in Sub-Saharan Africa: A multi-factorial problem”. Transfusion (2008).
  6. Diakité M., et al. “Connaissances et attitudes du personnel médical en matière de transfusion sanguine au Mali”. Transfusion Clinique et Biologique (2012).
  7. Aurelie MF., et al. “Prévalence des Infections Transmissibles par Transfusion Sanguine chez les Donneurs de Sang à l’Hôpital Central de Yaoundé – Cameroun”. Journal of Medical and Health Science (2019).
  8. Laperche S., et al. “Transfusion sanguine : en toute sécurité infectieuse”. Presse Medicale (2015).
  9. Laouina A., et al. “Prévalence des marqueurs infectieux transmissibles par transfusion chez les donneurs de sang au CRTS de Rabat (Maroc)”. Transfusion Clinique et Biologique (2016).
  10. Fenomanana J., et al. “Prévalence du trait drépanocytaire chez les donneurs de sang au centre régional de transfusion sanguine de la région Haute Matsiatra, Madagascar”. Pan African Medical Journal (2020).
  11. Allali S., et al. “Transfusing children with hemoglobinopathies”. Transfusion Clinique et Biologique (2019).
  12. Diarra AB., et al. Sécurité transfusionnelle et drépanocytose à Bamako, Mali. Séroprévalence des infections à VIH, VHB, VHC et allo-immunisation anti-Rh et Kell chez les drépanocytaires. Transfusion Clinique et Biologique (2013).
  13. Thurston GB., et al. “Effects of erythrocytapheresis transfusion on the viscoelasticity of sickle cell blood”. Clinical Hemorheology and Microcirculation (2004).
  14. Motaze ACN. “Dépistage néonatal de la drépanocytose au Cameroun: Etude rétrospective sur 5846 nouveau-nés au Centre Hospitalier d’Essos”. Semantic Scholar (2013).
  15. Ngwengi NY., et al. “Distribution of haemoglobin genotypes, knowledge, attitude and practices towards sickle cell disease among unmarried youths in the Buea Health District, Cameroon”. Pan African Medical Journal (2020).
  16. Antwi-Baffour S., et al. “Prevalence of hemoglobin S trait among blood donors: a cross-sectional study”. BMC Research Notes (2015).
  17. Garraud O. “How to reposition the benefice–risk balance to safely transfuse patients in non-vital situations?”. Transfusion Clinique et Biologique (2019).
  18. Tagny CT., et al. “Le groupe de recherches transfusionnelles d’Afrique francophone: Bilan des cinq premières années”. Transfusion Clinique et Biologique (2014).
  19. Tagny CT and Mbanya D. “The erythrocyte phenotype in ABO and Rh blood groups in blood donors and blood recipients in a hospital setting of Cameroon: Adapting supply to demand Global Surveillance View project Viral Discovery Project View project”. Revue Médicale de Bruxelles (2009).
  20. Bates I., et al. “Reducing replacement donors in Sub-Saharan Africa: challenges and affordability”. Transfusion Medicine (2007).
  21. World Medical Association. “Declaration of Helsinki, Ethical Principles for Scientific Requirements and Research Protocols”. Bulletin World Health Organizarion (2013).
  22. Whelton PK., et al. “2017 Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults”. Journal of the American College of Cardiology (2018).
  23. Obesity and overweight (2021).
  24. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. World Health Organization (‎2011).
  25. "Manuel des techniques de base pour le laboratoire médical". (1982): 435-448. World health organization (1982).
  26. Tagny CT., et al. “The blood donor in sub-Saharan Africa: a review”. Transfusion Medicine (2010).
  27. Mandisodza AR., et al. “Prevalence of HIV infection in school based and other young donors during the 2002 and 2003 period”. African Journal of Medicine and Medical Science (2006).
  28. Cunha L., et al. “Use of replacement blood donors to study the epidemiology of major blood-borne viruses in the general population of Maputo, Mozambique”. Journal of Medical Virology (2007).
  29. Nébié., et al. “Lack of knowledge of blood donors in Burkina Faso (West Africa); Potential obstacle to transfusion security”. Transfusion Clinique et Biologique (2007).
  30. Tagny CT., et al. “Characteristics of blood donors and donated blood in sub-Saharan Francophone Africa”. Transfusion (2009).
  31. Rajab J., et al. “Blood donor haematology parameters in two regions of Kenya”. East Africa Medical Journal (2005).
  32. Salah H E. “Demographical Pattern of Blood Donors and PreDonation Deferral Causes in Dhahran, Saudi Arabia”. Journal of Blood Medicine (2020).
  33. V Yousefinejad., et al. “The Prevalence of High Blood Pressure in Blood Donors and the Relevant Factors in Sanandaj Blood Transfusion Center In 1384”. Scientific Journal Iran Blood Transfusion Organization (2007).
  34. Ngongang Ouankou C., et al. “Severe high blood pressure recently diagnosed in an urban milieu from Subsahelian Africa: Epidemiologic, clinical, therapeutic and evolutionary aspects”. Annals of Cardiology and Angeiology (Paris) (2019).
  35. Felix CE., et al. “Evaluation of body mass index, hematocrit, erythrocyte sedimentation rate and total protein in voluntary and commercial blood donors in Nigeria: Advocating for simultaneous screening for nutritional status”. International Journal of Blood Transfusion and Immunohematology (2017).
  36. Sparrow RL., et al. “Higher donor body mass index is associated with increased hemolysis of red blood cells at 42-days of storage: A retrospective analysis of routine quality control data”. Transfusion (2021).
  37. Basavarajegowda A. “Body Mass Index as Predictor of Vasovagal Reactions in First Time Male Blood Donors”. Hematology and Transfusion International Journal (2016).
  38. Van Den Hurk K., et al. “Blood donors’ physical characteristics are associated with pre-and post-donation symptoms-Donor InSight”. Blood Transfusion (2017).
  39. Murphy EL., et al. “BMI and obesity in US blood donors: a potential public health role for the blood centre”. Public Health Nutrition (2012).
  40. Hamed CT., et al. “Frequencies and ethnic distribution of ABO and Rh (D) blood groups in Mauritania: Results of first nationwide study”. International Journal of Immunogenetics (2012).
  41. N Habti., et al. “ABO polymorphism in blood donors in Morocco”. Transfusion Clinique et Biologique (2004).
  42. Tayou Tagny C., et al. “Le centre de transfusion, le donneur de sang et le sang donné dans les pays d’Afrique francophone”. Transfusion Clinique et Biologique (2009).
  43. Vanessa I., et al. “Séroprévalence et facteurs associés au VIH et aux hépatites virales B et C dans la ville de Bafoussam au Cameroun”. Pan African Medical Journal (2015).
  44. Tadongfack TD., et al. “Hepatitis b infection in the rural area of dschang, cameroon: Seroprevalence and associated factors”. Pan African Medical Journal (2020).
  45. Ansah P., et al. “Sickle Cell Trait among Blood Donors in the Ho Teaching Hospital Ghana: A Laboratory-Based Cross-Sectional Study”. Journal of Haematology and Clinical Thererapy (2020).
  46. Batina‐Agasa S., et al. “Sickle cell trait among blood donors in the democratic republic of the Congo: which transfusion policy for Sickle cell patients?” ISBT Science Series (2021).


Citation: Thomas Djifack Tadongfack., et al. “Obstacles to Blood Donation and the Prevalence of Sickle Cell Trait at the Bafoussam Regional Hospital Blood Bank, West - Cameroon”.Acta Scientific Medical Sciences 7.8 (2023): 09-16.


Copyright: © 2023 Thomas Djifack Tadongfack., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US