QV Kazaryan*, NG Hunanyan, TA Piliposyan, RG Chibukhchyan and AV Mkrtchyan

L.A. Orbeli Institute of Physiology, NAS RA, Yerevan, Armenia

*Corresponding Author: QV Kazaryan, L.A. Orbeli Institute of Physiology, NAS RA, Yerevan, Armenia.

Received: March 31, 2023; Published: April 25, 2023

Abstract

The relationship between the spontaneous electrical activities of paired fallopian tubes, and, accordingly, each of them with the uterine corpus, was studied by stepwise transections. The stability of rhythmogenesis of the left uterine horn was revealed in case of the both experimental conditions- when the right horn or the left horn itself was isolated. Transection of the right fallopian tube contributes to decrease in the values of such parameters of activity as the amplitude and rise-rate of action potentials (almost by 10 %) in the left fallopian tube. It has also been shown that the values of similar parameters of electrical activity were decreased in the uterine corpus after transection of the right (the amplitude - by 29.83% and the rise - rate - by 17.6%), then the left (by 36.67% and 16 % respectively) uterine horns.

Based on the results obtained in these experiments, we assume that the left uterine horn has a unique stability of automatism and, at the same time, it is in a certain functional relationship with the uterine corpus.

 Keywords: Myometrium; Spontaneous Electrical Activity; Left and Right Fallopian Tubes (Uterine Horns); Uterine Corpus; Transection; Relationship

References

1. Mancinelli R., et al. “In vitro motility of non-pregnant rat uterine horns”. Quarterly Journal of Experimental Physiology 4 (1988): 459-469.
2. Maul H., et al. “The physiology of uterine contractions”. Clinical Perinatology4 (2003): 665-676.
3. Crane LH and Martin L. “In vivo myometrial activity in the rat during the oestrous cycle: studies with the novel technique of video laparoscopy”. Reproduction, Fertility and Development 2 (1991b): 185-199.
4. Garfield RE and Maner WL. “Physiology and electrical activity of uterine contractions”. Seminars in Cell and Developmental Biology 3 (2007): 289-295.
5. Blackburn ST. “Maternal, fetal, and neonatal physiology: a clinical perspective (5^th)”. Saunders Elsevier (2016).
6. Shmygol A., et al. “Spontaneous electrical activity in subpopulation of freshly isolated rat uterine myometrial cells”. University of Cambridge, Journal of Physiology 555P (2004): 167.
7. Kazaryan KV., et al. “The role of ovarian horn area in regulation of spontaneous electrical activity of the rhythmogenic areas in myometrium”. Journal of Evolutionary Biochemistry and Physiology5 (2017): 368-375.
8. Lammers WJ EP., et al. “Patterns of electrical propagation in the intact pregnant guinea pig uterus”. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 3 (2008): R919-R928.
9. Hunanyan NG., et al. “The study of spontaneous electrical activity registered from different areas of the rat uterus”. Materials of the conference: "The modern problems of integrative activity and plasticity of the nervous system". Yerevan (2009): 306-311.
10. Rabotti C., et al. “Electrohysterographic analysis of uterine contraction propagation with labor progression: a preliminary study”. Conf. Proc. IEEE Eng. Med. Biol Soc. (2007): 4315-4318.
11. Kazaryan KV., et al. “Role of oxytocin in activation of spontaneous electrical activity of uterine corpus and uterine tubes in non-pregnant rats”. Russian Journal of Evolutionary Biochemistry and Physiology3 (2011): 284-291.
12. Hunanyan NG and Kazaryan KV. “Electrophysiological characteristics of different areas of the uterus and uterine horns in rats”. In: Materials of the conference: "Physiological mechanisms of organisms functional regulation" Yerevan, 3 (2012): 29-334.
13. Kazaryan KV., et al. “Identification of the characteristics of spontaneous electrical activity in the myometrial rythmogenic areas in rats”. Journal of Evolutionary Biochemistry and Physiology5 (2015): 340-346.
14. Shmygol A., et al. “Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility”. Acta Pharmacologica Sinica7 (2006): 827-832.
15. Kazaryan KV., et al. “Characteristics of the electrophysiological properties of the uterus and periuterine horn areas in rats”. Russian Journal of Physiology 96 (2010): 981-987.
16. Kazaryan KV., et al. “Spontaneous electrical activity of fallopian tubes in rats”. Russian Journal of Evolutionary Biochemistry and Physiology 3 (2020): 245-250.
17. Kazaryan KV., et al. “Synchronization of characteristics of action potentials in rhythmogenic areas of miometrium under the influence of oxytocin”. Russian Journal of Physiology3 (2016): 317-329.
18. Buhimschi CS., et al. “Effect of stimulatory and inhibitory drugs on uterine electrical activity measured noninvasively from the abdominal surface of pregnant rats”. American Journal of Obstetrics and Gynecology 1 (2000): 68-75.
19. Parkington HC and Coleman HA. “Excitability in uterine smooth muscle”. Frontiers of Hormone Research 27 (2001): 179-200.
20. Cavaco-Goncalves S., et al. “Increased cervical electrical activity during oestrus in progestagen treated ewes: Possible role in sperm transport”. Animal Reproduction Science3-4 (2006): 360-365.
21. Coleman HA., et al. “Changes in the mechanisms involved in uterine contractions during pregnancy in guinea-pigs”. Journal of Physiology3 (2000): 785-798.
22. Sarkisyan RSH., et al. “Modern microprocessor equipment developed for conduction of electrophysiological studies”. International scientific technological exhibition “Digitec Expo14”. 1-3 October, Yerevan (2014).

Citation

Citation: QV Kazaryan., et al. “The Role of The Fallopian Tube in Performance Of The Main Myometrial Functions”.Acta Scientific Medical Sciences 7.5 (2023): 191-196.

Copyright

Copyright: © 2023 QV Kazaryan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.