Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 7 Issue 5

Antibacterial Effect of Herbal Extracts on Escherichia coli Isolates from Urinary Tract Infection

Anapaulla Pereira e Oliveira1, Ana Flávia Ribeiro da Silva2, Isabela Gonçalves da Silva3, Yago de Sousa Castro3, Samella Crystina Silva3, Rafaela Costa Oliveira3 and Sérgio Eustáquio Lemos da Silva3*

1Lutheran University of Brazil, ULBRA, Brazil
2Universidade Presidente Antõnio Carlos, UNIPAC, Brazil
3Centro Universitário do Triângulo, UNITRI, Brazil

*Corresponding Author: Sérgio Eustáquio Lemos da Silva, Centro Universitário do Triângulo, UNITRI, Brazil.

Received: April 12, 2023; Published: April 21, 2023


Escherichia coli is seen as an important bacterium that causes diarrhea in humans and animals. In addition to being associated with intestinal infections, it is commonly associated with urinary tract infections. As a treatment, several antibiotics are used to control these infections, but over time the development of microorganisms resistant to their active principles has been observed, causing medicine to seek new treatment alternatives. Among the most widely used is herbal medicines, compounds made from the extract of medicinal plants. Punica granatum is an herbal medicine well known for its anti-inflammatory action and high antimicrobial content. Thus, it is important to investigate whether Punica granatum extract has antimicrobial action on strains of the bacterium Escherichia coli, inhibiting its growth. This study aimed to analyze the inhibition of Punica granatum extract on the growth of an isolate of Escherichia coli from a patient with urinary tract infection. The isolates of Escherichia coli were donated by the Laboratory of Clinical Analysis San Francisco. The method used for the distribution of the extracts in the plates was the diffusion of discs in agar. The experiment was carried out in triplicate. It was observed that there was no inhibition of the growth of the bacterium Escherichia coli in any concentration of the tested extracts. Between the treatments designed and applied, there was a significant difference, the positive control presented efficiency in the inhibition of Escherichia coli, while the negative control did not present antimicrobial activity, as expected. In view of the results obtained, it was concluded that the aqueous extracts of the fruit of Punica granatum did not inhibit the growth of the bacterium Escherichia coli, but there was a reduction of bacterial growth in the treatments with the peel and mesocarp of the fruit, showing that in both there is antimicrobial activity on isolates of Escherichia coli.

 Keywords: Antibiogram; Punica granatum; Inhibition Halos; Uroculture


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Citation: Sérgio Eustáquio Lemos da Silva., et al. “Antibacterial Effect of Herbal Extracts on Escherichia coli Isolates from Urinary Tract Infection”.Acta Scientific Medical Sciences 7.5 (2023): 154-159.


Copyright: © 2023 Sérgio Eustáquio Lemos da Silva., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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