Surendra Kumar Verma¹*, Vartika Jain² and SS Katewa³

¹Department of Medicine, Pacific Medical College and Hospitals, Udaipur, Rajasthan and Former Chief Investigator, Indigenous Drug Research Centre, RNT Medical College, Udaipur, India
²Department of Botany, Govt. Meera Girls College, Udaipur, Rajasthan, India
³Former Professor and Head, Department of Botany, Mohanlal Sukhadia University, Udaipur, Rajasthan, India

*Corresponding Author: Surendra Kumar Verma, Department of Medicine, Pacific Medical College and Hospitals, Udaipur, Rajasthan and Former Chief Investigator, Indigenous Drug Research Centre, RNT Medical College, Udaipur, India.

Received: November 21, 2022; Published: December 29, 2022

Abstract

Background: Spices and condiments are reported to possess many health-beneficial activities. Cinnamon (Cinnamommum verum J. Presl.) is a well-known spice used in preparation of many cuisines and sweet dishes. Several scientific studies have reported its protective role in modification of risk factors associated with cardio-vascular diseases. Traditional medicine also recommends its use for treatment of heart disease. In view of all this, its bark powder was evaluated for its effect on blood lipids, fibrinolysis, fibrinogen and total antioxidant status in patients with ischemic heart disease.

Methods: Forty individuals (50-70 years) with ischemic heart disease were selected for the study and divided into two groups of twenty each. Group I (Treated) received 3 g Cinnamon powder in two divided doses while Group II (Placebo) received matched placebo capsules for four weeks. Blood samples were collected initially and at the end of four weeks for analysis of lipid profile, fibrinogen, fibrinolytic activity and total antioxidant status.

Results: Administration of Cinnamon significantly (p < 0.001) reduced atherogenic lipids without significant alteration in HDL-cholesterol. A statistically significant enhancement in Plasma fibrinolytic activity (p < 0.001) and serum total antioxidant status (p < 0.05) was observed at the end of the study. The placebo group however did not show significant alteration in these parameters. It was tolerated well without any untoward effects.

Conclusion: Four weeks supplementation of Cinnamon (1.5g twice daily) to patients having ischemic heart disease favorably affects various lipid parameters, fibrinolytic activity and total antioxidant status in a statistically significant manner.

Keywords: Non-HDL-Cholesterol; Atherogenic Index; Cinnamaldehyde; Cholesterol; Atherosclerosis

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Citation

Citation: Surendra Kumar Verma., et al. “Effect of Cinnamon (Cinnamommum verum J. Presl.) on Blood Lipids, Fibrinogen, Fibrinolysis, and Total Antioxidant Status in Patients with Ischemic Heart Disease”.Acta Scientific Medical Sciences 7.1 (2023): .

Copyright

Copyright: © 2022 Surendra Kumar Verma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.