Starch-based Hemostatic Powder as a Novel Anti-adhesive Agent
Alp Yildiz1*, Yavuz Pirhan2, Caglar Ozcelik1, Furkan Savas3 and Aybala Yildiz4
1Department of General Surgery, Yildirim Beyazit University Yenimahalle Training and Research Hospital, Ankara, Turkey
2Department of General Surgery, Amasya University School of Medicine, Amasya, Turkey
3Department of General Surgery, Bilkent City Hospital, Ankara, Turkey
4Department of General Surgery, Ankara Oncology Training and Research Hospital, Ankara, Turkey
*Corresponding Author: Alp Yıldız, Department of General Surgery, Yildirim Beyazit University Yenimahalle Training and Research Hospital, Ankara, Turkey.
July 01, 2022; Published: September 05, 2022
Introduction: Adhesions develop after up to 97% of abdominal surgery causing chronic pain and intestinal obstruction. Only a few of hemostatic agents are available for adhesion prevention [2-4]. In this retrospective study we investigated the effectivity of starch based hemostatic powder (SBHP) on preventing postoperative intraabdominal adhesions.
Patients and Methods: This retrospective study comprises 54 patients aged 18-67, who underwent second look laparotomy/laparoscopy in the period from 2018 and 2021. Only patients with a second look surgery were included in the study. Group-1 had been applied hemostatic agent in initial operation as Group-2 had not been applied any agents. On second-look laparotomy adhesions has observed and recorded.
Results: Both median adhesion severity and extent scores in Group-1 were 0.4, and 1.8 in Group-2. The statistical evaluation shows that both severity and extent were significantly reduced from Group-2 to Group-1 when SBHP was used.
Conclusion: In the light of the high efficacy observed in the present study we recommend to take SBHP into consideration as anti-adhesive agent additional to hemostatic product.
Keywords: Adhesion; Surgery; Anti-adhesive
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