Genetic Polymorphism Can Play a Major Role in Distance Preference by Elite Stayers
IR Mavlyanov, AKh Ashirmetov, NM Rakhimova* and ST Yulchiev
Republican Scientific and Practical Center of Sports Medicine at the National Olympic Committee of Uzbekistan, Uzbekistan
*Corresponding Author: NM Rakhimova, Republican Scientific and Practical Center of Sports Medicine at the National Olympic Committee of Uzbekistan, Uzbekistan.
June 08, 2022; Published: July 15, 2022
This study assessed the association between elite track and field athletes' preference for distance running and variants of 10 genes previously associated with an individual's endurance, power or strength status.
Athletes were divided into 3 groups according to preference for short (0.8 and 1.5 km), medium (1.5 - 21.1 km) and long (21.1 and 41.1 km) distances. The study analyzed the frequency of detection of the corresponding alleles and the " total genotype score" (TGS) of such genes as: ACE I/D, ACTN3 C/T, AMPD1 C/T, PPARA G/C, PPARG2 C/G, MTHFR A/C, HIF1A C/T, ADRB2 C>G, ADRB2 G>A, NOS3 C/T, relative to non-athletes.
It was found that the frequency of alleles in terms of power and strength, as well as TGS in elite stayers who prefer short distances, were higher than in marathon runners and the control group. The same indicators regarding endurance showed the opposite picture. Alleles of the NOS3 and ACTN3 genes were noted as promising genetic markers for all stayers, and for marathon runners AMPD1 as well and HIF1A as the allele of endurance. Whereas, for middle-distance runners, the power allele PPARA was added, and for athletes who prefer short distances, PPARA, MTHFR and ACE were also added.
Keywords: Sports Genetics; Elite Athletes; Genetic Polymorphism; Running Distance; Endurance; Power; Strength; Marathon
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