Bréhima Traoré¹*, Modibo Coulibaly², Oumar Guindo³, Djibril Traoré¹, Abdoulaye Traoré⁵, Kiffery Ibrahim Keita¹, Aly Boubacar Diallo⁹, Souleymane Sanogo⁷, Alhassane Traoré⁴, Mathias Diassana¹, Korotimou Mallé¹, Fodé Mory Keita¹, DK Dembele¹, Dramane Samaké⁶ and Yacaria Coulibaly⁸

¹General Surgery Department, Sominé Hospital DOLO in Mopti, Mali
²Medical Biology Laboratory Service, Sominé DOLO Hospital in Mopti, Mali
³Public Health Service, Sominé DOLO Hospital in Mopti, Mali
⁴Department of General Surgery, CHU Gabriel Touré, Mali
⁵Anesthesia/Resuscitation Department and Operating Theatre, Mali
⁶Medical Service, Sominé Dolo Hospital in Mopti, Mali
⁷Medical Imaging Department of the Luxembourg Mother and Child Hospital in Bamako, Mali
⁸Gabriel Touré University, Hospital Pediatric Surgery Department, Mali
⁹Sikasso Regional Hospital, General Surgery Department, Mali

*Corresponding Author: Bréhima Traoré, General Surgery Department, Sominé Hospital, DOLO in Mopti, Mali.

Received: April 07, 2022; Published: July 08, 2022

Abstract

We performed a 3-year retrospective and prospective study, from January 1, 2017 to December 31, 2019, carried out in the department of general surgery at Somine Hospital DOLO of Mopti. The objective of this study was to determine the frequency and the clinical and paraclinical features of amoebic abscess of the liver in a hospital setting. Subjects were selected based on the results of physical examination, ultrasound, amoebic serology and pus culture. For 7305 admissions, 32 cases of amoebic abscess of the liver were collected, which represents a hospital frequency of 0.4% and an incidence of 10 cases. The average age of subjects was 35 years in adults and 6 years in children. The sex ratio was 3.6. The most common clinical signs were fever (90.6%), hepatomegaly (81.3%) and nausea and/or vomiting (56.3%). The collections objectified by abdominal ultrasound were located in the right lobe in 78.1% of cases and unique in 87.5% of cases. Culture of the collection revealed 6.2% of active liver abscess with the presence of Entamoeba histolytica. The diagnosis of uncomplicated amoebic abscess of the faith was retained in 59.4% of cases. Amoebic abscess complicated by peritonitis, right pleurisy and parietal abscess was reported in 40.6% of cases. Among the complications, peritonitis was the most frequent with 46.1% followed by right pleurisy 23.1% and parietal abscess 15.4%. Medical treatment was exclusive in 12.5% of cases, a evacuating puncture under ultrasound guidance was necessary in 9.4% of cases. Surgery was performed in 78.1% of cases. The post-treatment clinical course was favorable from the outset in 90.6% of our patients with total emptiness on ultrasound and secondarily in 9.4% who progressed favorably after a second drainage plus antibiotic therapy. Multidisciplinary management of amoebic abscesses in the liver involving the infectious disease specialist, visceral surgeon, radiologist and biologist improves diagnosis, therapeutic management and patient follow-up.

Keywords: Amoebic Liver Abscess; Somine DOLO Hospital in Mopti; Type of Treatment; Clinical Course

References

1. Kantor M., et al. “Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development”. Canadian Journal of Gastroenterology and Hepatology (2018): 4601420.
2. Rashidul H., et al. “Amebiasis”. The New England Journal of Medicine 16 (2003): 1565-1573.
3. Tracy E Bercu., et al. “Amebic colitis: new insights into pathogenesis and treatment”. Current Gastroenterology Reports5 (2007): 429-433.
4. K Sacko., et al. “Les abcès hépatiques dans le département de pédiatrie du chu gabrieltouré de Bamako, Mali. une étude de 31 cas”. Journal of Medicine and Health Science4 (2019): 71-75.
5. Doumbia K épouseSamaké., et al. “l’abcès amibiens du foie : aspects cliniques et évolutifs au CHU Gabriel Touré de Bamako”. Mali Médical4 (2018): 23-25.
6. A Traoré., et al. “Abcès amibien du foie en chirurgie générale du CHU Gabriel Toure, Bamako, Mali”. Mali Médical4 (2014): 5-9.
7. A Halim., et al. “Aspects actuels de l’amibiase hépatique à Dakar. A propos de 48 observations”. Journal Africain d'Hépato-Gastroentérologie 10 (2016): 170-175.
8. Djoussou F., et al. “Abcès amibien du foie, Analyse de 20 observations et proposition d’un algorythmethérapeutique”. La Revue de Médecine Interne 24 (2003): 97-101.
9. A Ba., et al. “Particularités des abcès du foie chez l’enfant au Sénégal : description d’une série de 26 cas. Particularities of liver abscesses in children in Senegal: Description of a series of 26 cases”. Archives de Pédiatrie 5 (2016): 491-496.
10. Koumaré S., et al. “Aspects diagnostiques et thérapeutiques des abcès amibiens du foie dans le service de chirurgie "A " du CHU du Point "G". Mali Médical1 (2018): 1-5.
11. JR Ibara., et al. “Abcès du foie a germes pyogenes aspects cliniques, morphologiques et etiologiques à propos de 38 cas”. Médecine d'Afrique Noire2 (2000) : 92-96.
12. Zimogo ZS., et al. “Abcès amibiens du foie : expérience tropicale d’une pathologie peu observée en Europe”. Journal de Chirurgie Viscéral3 (2008): 300.
13. Oudou Njoya., et al. “Abcès amibien du foie à Yaoundé. Cahiers d'études et de recherches francophones”. Santé 2 (1999) : 119-122.
14. A Essomba., et al. “Les abdomens aigus d'étiologie parasitaire : analyse d'une série rétrospective de 135 casAcute abdomens of parasiticorigin: retrospectiveanalysis of 135 cases”. Annales de Chirurgie3 (2006): 194-197.
15. WS Nambei. “Anticorps IgG anti-Entamoeba histolytica chez des patients présentant un abcès amibien du foie à Bangui, République Centrafricaine”. CAMES SANTE 3.2 (2015): 23-27.
16. L Chiche., et al. “Abcès à pyogènes du foie. Diagnostic et prise en charge Pyogenic-liver abscess: Diagnosis and management”. Gastroentérologie Clinique et Biologique12 (2008): 1077-1091.
17. V Guittet., et al. “Les abcès hépatiques de l'enfant : étude rétrospective de 33 cas observés en Nouvelle-Calédonie de 1985 à 2003Hepatic abscesses in childhood: retrospective study about 33 cases observed in New-Caledoniabetween 1985 and 2003”. Archives de Pédiatrie9 (2004) : 1046-1053.
18. R Lebeau., et al. “Abcès amibien du foie au chu de Bouaké : étude diagnostique et thérapeutique à propos de 46 cas”. Mali Médical3 (2006) : 10-14.
19. Simon N., et al. “Une hépatopathiemultinodulairefébrile en zone tropicale”. Médecine Tropicale6 (2009): 603-605.
20. L Fievet., et al. “Abcès hépatique chez l’enfant : à propos d’un cas”. Archives de Pédiatrie5 (2012): 497-500.
21. N’goranK., et al. “Prise en charge multidisciplinaire des abcès amibiens du foie au CHU de Yopougon, Abidjan-Cote d’ivoire”. Pan Africain Medical Journal7 (2011): 11.
22. N Kouamé., et al. “Ponction échoguidée plus métronidazole versus métronidazole seul dans la prise en charge des abcès amibiens collectés de l’enfant”. Journal Africain d'Hépato-Gastroentérologie205 (2011).
23. Badouil Dabo G. “Abcès à pyogènes: à propos de 19 cas et revue de la littérature”. Le Bulletin de la Société de Pathologie Exotique 106 (2013): 334-359.
24. Shi S., et al. “Unique characteristics of pyogenic liver abscess of biliary origin”. Surgery5 (2016): 1316-1324.
25. M Dieng., et al. “Traitement des abcès du foie : l’expérience d’un service de chirurgie Générale”. Médecine d’Afrique Noire10 (2007): 513-519.
26. Ben Abdallah R., et al. “Abcès amibien du foie authentifié par PCR chez un resort issant indien”. Rev Tun Infectiol 2 (2009): 41-43.
27. Ryszard J. “Clinical manifestation and ultrasonography guide aspiration of amoebic Liver absess in St Walburge’sHospitol, Nyango”. Tanzania Tropical Doctor 32 (2002): 92-93.
28. Czerwonko ME., et al. “Pyogenic liver absess: current statuts and predictive factors recurrence and mortality of first episodes”. HPB12 (2016): 1023-1030.

Citation

Citation: Bréhima Traoré., et al. “Amoebic Liver Abscess in the Department of General Surgery at Somine Hospital DOLO of Mopti, Mopti, Mali”.Acta Scientific Medical Sciences 6.8 (2022): 36-42.

Copyright

Copyright: © 2022 Bréhima Traoré ., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.